Evidence map›Paper›PMID 34642823›Full record

Observational studyNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2022

Cognitive, behavioral, and psychological manifestations of COVID-19 in post-acute rehabilitation setting: preliminary data of an observational study.

Silvia Bonizzato, Ada Ghiggia, Francesco Ferraro, Emanuela Galante

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
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  6. Article
  7. Spontaneous recovery from post-COVID-19 brain fog.PCN reports : psychiatry and clinical neurosciences · 2024
    Article
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Review
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  15. Cognitive impairment in people with previous COVID-19 infection: A scoping review.Cortex; a journal devoted to the study of the nervous system and behavior · 2022
    Article
  16. Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Silvia BonizzatoDepartment of Psychology, University of Milan-Bicocca, Piazza dell'Ateneo Nuovo 1, Milan, Italy.
Ada GhiggiaDepartment of Psychology, University of Turin, Via Verdi 10, 10124, Turin, Italy. ada.ghiggia@unito.it.ORCID http://orcid.org/0000-0003-1347-9762
Francesco FerraroNeuro-Motor Rehabilitation Unit, Neuroscience Department, Azienda Socio Sanitaria Territoriale Di Mantova, via XXV Aprile 71, Bozzolo, Mantova, Italy.
Emanuela GalanteNeuro-Motor Rehabilitation Unit, Neuroscience Department, Azienda Socio Sanitaria Territoriale Di Mantova, via XXV Aprile 71, Bozzolo, Mantova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychological, emotional, and behavioral domains could be altered in COVID-19 patients and measurement of variables within these domains seems to be mandatory. Neuropsychological assessment could detect possible cognitive impairment caused by COVID-19 and the choice of appropriate tools is an important question. Aim of this exploratory study was to verify the effectiveness of an assessment model for patients with COVID-19. Twelve patients were enrolled and tested with Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Anxiety and Depression Short Scale (AD-R), and the Neuropsychiatry Inventory (NPI), at the time of their entrance (T0) and discharge (T1) from a rehabilitative unit. Moreover, a follow-up evaluation after 3 months (T2) has been conducted on eight patients. Results showed that at baseline (T0), 58.3% of the patients reported a score below cut-off at MMSE and 50% at MoCA. Although a significant amelioration was found only in NPI scores, a qualitative improvement has been detected at all tests, except for MoCA scores, in the T0-T1 trend analysis. A one-way repeated measures analysis of variance showed a significant variation in AD-R depression score, considering the three-assessment time (T0, T1, and T2). The evaluation and tracking over time of the impact of COVID-19 on cognitive, psychological, and behavioral domains has relevant implications for rehabilitation and long-term assistance needs planning. The choice of assessment tools should consider patients vulnerability and match the best compromise among briefness, sensitivity, and specificity.

Indexed as

Cognitive DysfunctionCOVID-19CognitionHumansMental Status and Dementia TestsNeuropsychological TestsPreliminary DataSARS-CoV-2Behavioral alterationsCOVID-19Neuropsychological deficitPsychological assessment

Identifiers

PMID34642823
PMCPMC8510572

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.