ArticleEuropean radiology2022
Histogram analysis of diffusion-weighted imaging and dynamic contrast-enhanced MRI for predicting occult lymph node metastasis in early-stage oral tongue squamous cell carcinoma.
Article in European radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 6 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 6 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Artificial Intelligence-Driven MRI for Cervical Nodal Metastasis Detection in Oral Squamous Cell Carcinoma: A Hierarchical Meta-Analysis of Diagnostic Accuracy.Head & neck · 2026Pooled it
- Diagnostic imaging modalities to detect regional nodal involvement in oral squamous cell carcinoma: a systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Pooled it
- Application of artificial intelligence and radiomics in the prediction of lymph node metastasis and tumour grading of oral cancer - a systematic review and meta analysis.BMC oral health · 2026Pooled it
- Radiomics-Based Diagnosis in Dentomaxillofacial Radiology: A Systematic Review.Journal of imaging informatics in medicine · 2025Pooled it
- Diagnostic accuracy of radiomics and artificial intelligence models in diagnosing lymph node metastasis in head and neck cancers: a systematic review and meta-analysis.Neuroradiology · 2025Pooled it
- Application of CT and MRI images based on artificial intelligence to predict lymph node metastases in patients with oral squamous cell carcinoma: a subgroup meta-analysis.Frontiers in oncology · 2024Pooled it
- Development and validation: a whole-tumor histogram model based on intravoxel incoherent motion diffusion-weighted imaging for diagnosing tumor deposits in rectal cancer.Abdominal radiology (New York) · 2026Article
- Deep learning radiomics based on multimodal MRI for preoperative prediction of N stage in tongue squamous cell carcinoma: a multicenter study.BMC oral health · 2026Article
- Association between histogram parameters of T2 weighted MRI data, WHO grade, tumor proliferation index and selected molecular markers in low-grade glioma.Frontiers in radiology · 2026Article
- Advanced diffusion-relaxation imaging for tumoral differentiation and metastasis prediction in oral tongue cancer.European radiology experimental · 2025Article
- Histogram-based analysis for confocal microscope images with immunofluorescent staining: A graphical-user-interface tool.MethodsX · 2025Article
- Sinonasal adenoid cystic carcinoma: preoperative apparent diffusion coefficient histogram analysis in prediction of prognosis and Ki-67 proliferation status.Japanese journal of radiology · 2025Article
- Whole-tumor histogram analysis of multiple non-Gaussian diffusion models at high b values for assessing cervical cancer.Abdominal radiology (New York) · 2024Article
- Whole-tumor histogram analysis of postcontrast T1-weighted and apparent diffusion coefficient in predicting the grade and proliferative activity of adult intracranial ependymomas.Neuroradiology · 2024Article
- Correlation of MRI quantitative perfusion parameters with EGFR, VEGF and EGFR gene mutations in non-small cell cancer.Scientific reports · 2024Article
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- Whole-tumor histogram analysis of apparent diffusion coefficient maps with machine learning algorithms for predicting histologic grade of sinonasal squamous cell carcinoma: a preliminary study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
- Development and validation of apparent diffusion coefficient histogram-based nomogram for predicting malignant transformation of sinonasal inverted papilloma.Dento maxillo facial radiology · 2023Article
- Radiomics-Based Analysis in the Prediction of Occult Lymph Node Metastases in Patients with Oral Cancer: A Systematic Review.Journal of clinical medicine · 2023Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesTo investigate the feasibility of whole-tumor histogram analysis of diffusion-weighted imaging (DWI) and dynamic contrast-enhanced (DCE) MRI for predicting occult lymph node metastasis (LNM) in early-stage oral tongue squamous cell cancer (OTSCC). MATERIALS AND
methodsThis retrospective study included 55 early-stage OTSCC (cT1-2N0M0) patients; 34 with pathological LNM and 21 without. Eight whole-tumor histogram features were extracted from quantitative apparent diffusion coefficient (ADC) maps and two semi-quantitative DCE parametric maps (wash-in and wash-out). The clinicopathological factors and histogram features were compared between the two groups. Stepwise logistic regression was used to identify independent predictors. Receiver operating characteristic curves were generated to assess the performances of significant variables and a combined model for predicting occult LNM.
resultsMRI-determined depth of invasion and ADC
conclusionsWhole-tumor histogram analysis of ADC and wash-in maps is a feasible tool for preoperative evaluation of cervical node status in early-stage OTSCC. KEY POINTS: • Histogram analysis of parametric maps from DWI and DCE-MRI may assist the prediction of occult LNM in early-stage OTSCC. • ADC
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