Evidence map›Paper›PMID 34642692›Full record

ArticlebioRxiv : the preprint server for biology2021

Longitudinal characterization of circulating neutrophils uncovers distinct phenotypes associated with disease severity in hospitalized COVID-19 patients.

Thomas J LaSalle, Anna L K Gonye, Samuel S Freeman, Paulina Kaplonek, Irena Gushterova, Kyle R Kays, Kasidet Manakongtreecheep, Jessica Tantivit, Maricarmen Rojas-Lopez, Brian C Russo and 20 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

30 authors at 4 institutions in 1 country.

Thomas J LaSalle
Anna L K Gonye
Samuel S Freeman
Paulina Kaplonek
Irena Gushterova
Kyle R Kays
Kasidet Manakongtreecheep
Jessica Tantivit
Maricarmen Rojas-Lopez
Brian C Russo
Nihaarika Sharma
Molly F Thomas
Kendall M Lavin-Parsons
Brendan M Lilly
Brenna N Mckaig
Nicole C Charland
Hargun K Khanna
Carl L Lodenstein
Justin D Margolin
Emily M Blaum
Paola B Lirofonis
Abraham Sonny
Roby P Bhattacharyya
Blair Alden Parry
Marcia B Goldberg
Galit Alter
Michael R Filbin
Alexandra Chloe Villani
Nir Hacohen
Moshe Sade-Feldman
Broad Institute · USMassachusetts General Hospital · USHarvard University · USRagon Institute of MGH, MIT and Harvard · US

Funding

Training Program in Bioinformatics and Integrative GenomicsT32HG002295 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Peter J Park · 2001 to 2026
$15.8M
NHGRI NIH HHS T32 HG002295
6 · The paper itself

Abstract

Multiple studies have identified an association between neutrophils and COVID-19 disease severity; however, the mechanistic basis of this association remains incompletely understood. Here we collected 781 longitudinal blood samples from 306 hospitalized COVID-19

Identifiers

PMID34642692
PMCPMC8509090
OpenAlexW3203285287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.