Evidence map›Paper›PMID 34642415›Full record

Observational studyScientific reports2021

Antibodies against phosphorylcholine in hospitalized versus non-hospitalized obese subjects.

Amra Jujić, J Korduner, H Holm, G Engström, E Bachus, P Bhattacharya, P M Nilsson, Johan Frostegård, M Magnusson

Open access · goldAbstract readComparative StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Multitarget mechanisms of the herb pairFrontiers in pharmacology · 2026
    Article
  2. Do human B-1 lymphocytes truly exist?Frontiers in immunology · 2026
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Amra JujićDepartment of Clinical Sciences, Clinical Research Centre, Lund University, Room 60-12-009, Box 50332, 202 13, Malmö, Sweden. amra.jujic@med.lu.se.
J KordunerDepartment of Clinical Sciences, Clinical Research Centre, Lund University, Room 60-12-009, Box 50332, 202 13, Malmö, Sweden.
H HolmDepartment of Clinical Sciences, Clinical Research Centre, Lund University, Room 60-12-009, Box 50332, 202 13, Malmö, Sweden.
G EngströmDepartment of Clinical Sciences, Clinical Research Centre, Lund University, Room 60-12-009, Box 50332, 202 13, Malmö, Sweden.
E BachusDepartment of Clinical Sciences, Clinical Research Centre, Lund University, Room 60-12-009, Box 50332, 202 13, Malmö, Sweden.
P BhattacharyaInstitute of Environmental Medicine, Karolinska Institutet, IMM, Nobels väg 13, 17165, Stockholm, Sweden.
P M NilssonDepartment of Clinical Sciences, Clinical Research Centre, Lund University, Room 60-12-009, Box 50332, 202 13, Malmö, Sweden.
Johan Frostegård *Institute of Environmental Medicine, Karolinska Institutet, IMM, Nobels väg 13, 17165, Stockholm, Sweden. johan.frostegard@ki.se.
M Magnusson *Department of Clinical Sciences, Clinical Research Centre, Lund University, Room 60-12-009, Box 50332, 202 13, Malmö, Sweden.
Lund University · SEKarolinska Institutet · SESkåne University Hospital · SENorth-West University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity associates with reduced life expectancy, type 2 diabetes, hypertension and cardiovascular disease, and is characterized by chronic inflammation. Phosphorylcholine (PC) is an epitope on oxidized low-density lipoprotein, dead cells and some microorganisms. Antibodies against PC (anti-PC) have anti-inflammatory properties. Here, we explored the role of anti-PC in hospitalized versus non-hospitalized obese. One-hundred-and-twenty-eight obese (BMI ≥ 30 kg/m

Indexed as

AgedCross-Sectional StudiesDiabetes Mellitus, Type 2FemaleHospitalizationHumansImmunoglobulin GImmunoglobulin MLogistic ModelsMaleMetabolic SyndromeMiddle AgedObesityPhosphorylcholineRisk FactorsImmunoglobulin GImmunoglobulin MPhosphorylcholine

Identifiers

PMID34642415
PMCPMC8511239
OpenAlexW3205120897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.