Evidence map›Paper›PMID 34642275›Full record

ArticleJournal of neurogastroenterology and motility2021

Clinical Characteristics of Esophageal Motility Disorders in Patients With Heartburn.

Satsuki Takahashi, Tomoaki Matsumura, Tatsuya Kaneko, Mamoru Tokunaga, Hirotaka Oura, Tsubasa Ishikawa, Ariki Nagashima, Wataru Shiratori, Naoki Akizue, Yuki Ohta and 9 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurogastroenterology and motility, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Satsuki TakahashiDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Tomoaki MatsumuraDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Tatsuya KanekoDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Mamoru TokunagaDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Hirotaka OuraDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Tsubasa IshikawaDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Ariki NagashimaDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Wataru ShiratoriDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Naoki AkizueDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Yuki OhtaDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Atsuko KikuchiDepartment of Clinical Engineering Center, Chiba University Hospital, Chiba, Japan.
Mai FujieDepartment of Clinical Engineering Center, Chiba University Hospital, Chiba, Japan.
Keiko SaitoDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Kenichiro OkimotoDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Daisuke MaruokaDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Tomoo NakagawaDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Makoto AraiDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Jun KatoDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Naoya KatoDepartment of Gastroenterology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Chiba University · JPChiba University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsEsophageal motility disorders (EMDs) contribute to the pathophysiology of gastroesophageal reflux disease. However, the causes of EMDs and their impact on gastroesophageal reflux disease-associated symptoms remain unknown. This study aims to elucidate clinical features associated with various types of EMDs in patients with heartburn symptoms.

methodsOf the 511 patients who underwent high-resolution manometry, 394 who were evaluated for heartburn symptoms were examined. Patients subjected to high-resolution manometry were classified into 4 groups: outflow obstruction group, hypermotility group, hypomotility group, and normal motility group. Symptoms were evaluated using 3 questionnaires. Patient characteristics and symptoms for each EMD type were compared with those of the normal motility group.

resultsOf the 394 patients, 193 (48.9%) were diagnosed with EMDs, including 71 with outflow obstruction, 15 with hypermotility, and 107 with hypomotility. The mean dysphagia score was significantly higher in each of the 3 EMD groups compared with those with normal motility. The mean acid reflux and dyspepsia scores were significantly lower in the outflow obstruction group (

conclusionsThe results of our study indicate that different EMDs have distinct characteristics. Cigarette smoking and high body mass index were associated with esophageal hypermotility. Assessment of the dysphagia symptom scores may help identify patients with EMDs.

Indexed as

Esophageal motility disordersGastroesophageal refluxManometry

Identifiers

PMID34642275
PMCPMC8521463
OpenAlexW3207527001

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.