Evidence map›Paper›PMID 34642268›Full record

ReviewJournal of neurogastroenterology and motility2021

Brain to Belly: Abdominal Variants of Migraine and Functional Abdominal Pain Disorders Associated With Migraine.

Léa LenglarT, Caroline Caula, Thomas Moulding, Annabel Lyles, Delphine Wohrer, Luigi Titomanlio

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of neurogastroenterology and motility, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Transcutaneous vagus nerve stimulation as a potential novel treatment for cyclic vomiting syndrome: a first case report.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. The Role of the Human Microbiome in the Pathogenesis of Pain.International journal of molecular sciences · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Léa LenglarTDepartment of Pediatric Emergency Care, APHP - Hopital Robert Debré, Paris, France.
Caroline CaulaDepartment of Pediatric Emergency Care, APHP - Hopital Robert Debré, Paris, France.
Thomas MouldingDepartment of Specialty and Integrated Medicine, The Leeds Teaching Hospitals, NHS Trust, Leeds, UK.
Annabel LylesDepartment of Oncology, The Leeds Teaching Hospitals, NHS Trust, Leeds, UK.
Delphine WohrerDepartment of Pediatric Emergency Care, APHP - Hopital Robert Debré, Paris, France.
Luigi TitomanlioDepartment of Pediatric Emergency Care, APHP - Hopital Robert Debré, Paris, France.
Hôpital Robert-Debré · FRLeeds Teaching Hospitals NHS Trust · GBAssistance Publique – Hôpitaux de Paris · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Migraine is one of the most frequent causes of primary headache and 9% of children suffer from migraines. Most children will continue to experience migraine attacks as adults, therefore it is imperative that we have a thorough understanding of this major health issue. This article considers the so-called abdominal variants of migraine, which are more commonly seen in children rather than adults: abdominal migraine, cyclic vomiting syndrome, and infantile colic. Other functional abdominal pain disorders such as irritable bowel syndrome and functional dyspepsia have also been linked to migraine in clinical studies. The common pathophysiological root of these diseases seems to be the gut-brain axis mechanism. Abdominal variants of migraine are considered pediatric precursors of migraine whereas the functional abdominal pain disorders related to migraine seem to share a pathophysiological root with no temporarily link as for today. In this review we aim to describe the epidemiological background, the current pathophysiological theories and the relationship of each disease to migraine. This review is the first to compile abdominal variants of migraine and functional abdominal pain disorders associated with migraine and we endeavor to elucidate the broad spectrum of migraine-related episodes in children.

Indexed as

Abdominal painChildGastrointestinal microbiomeMigraine disorders

Identifiers

PMID34642268
PMCPMC8521460
OpenAlexW3205091366

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.