Evidence map›Paper›PMID 34642254›Full record

ArticleStroke and vascular neurology2022

Quantitative angiographic haemodynamic evaluation of bypasses for complex aneurysms: a preliminary study.

Junlin Lu, Chao Xue, Xulin Hu, Yuanli Zhao, Dong Zhang, Xiaolin Chen, Ji Zong Zhao

Open access · goldAbstract read
In one paragraph

Article in Stroke and vascular neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Junlin LuNeurosurgery, Beijing Tiantan Hospital, Beijing, People's Republic of China.ORCID 0000-0003-4879-0729
Chao XueDepartment of Industrial Engineering, Tsinghua University, Beijing, People's Republic of China.
Xulin HuChengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, People's Republic of China.
Yuanli ZhaoNeurosurgery, Beijing Tiantan Hospital, Beijing, People's Republic of China.
Dong ZhangNeurosurgery, Beijing Tiantan Hospital, Beijing, People's Republic of China.
Xiaolin ChenNeurosurgery, Beijing Tiantan Hospital, Beijing, People's Republic of China xiaolinchen488@hotmail.com.
Ji Zong ZhaoNeurosurgery, Beijing Tiantan Hospital, Beijing, People's Republic of China.
Beijing Tian Tan Hospital · CNChinese Academy of Sciences · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOpen microsurgery, often with bypass techniques, is indispensable for complex aneurysms. To date, it remains unknown whether arterial anatomy or quantitative blood flow measurements can predict insufficient flow-related stroke (IRS). The present study aimed to evaluate the risk factors for IRS in patients treated with open microsurgery with bypass procedures for complex internal carotid artery aneurysms.

methodsPatients with complex aneurysms undergoing bypass surgery were retrospectively reviewed. The recipient/donor flow index (RDFI) was preoperatively evaluated using colour-coding angiography. RDFI was defined as the ratio of the cerebral blood volume of the recipient and donor arteries. The sizes of the recipient and donor arteries were measured. The recipient/donor diameter index (RDDI) was then calculated. IRS was defined as the presence of new postoperative neurological deficits and infarction on postoperative CT scans. We assessed the association between RDFI and other variables and the IRS.

resultsTwenty patients (38±12 years) were analysed. IRS was observed in 12 patients (60%). Patients with postoperative IRS had a higher RDFI than those without postoperative IRS (p<0.001). RDDI was not significantly different between patients with and without IRS (p=0.905). Patients with RDFI >2.3 were more likely to develop IRS (p<0.001).

conclusionQuantitative digital subtraction angiography enables preoperative evaluation of cerebral blood volume. RDFI >2.3, rather than RDDI, was significantly associated with postoperative IRS. This preoperative evaluation allows appropriate decisions regarding the treatment strategy for preventing postoperative IRS.

Indexed as

Cerebral RevascularizationIntracranial AneurysmAngiographyHemodynamicsHumansRetrospective Studiesaneurysmangiographystroke

Identifiers

PMID34642254
PMCPMC8899645
OpenAlexW3206600231

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.