Evidence map›Paper›PMID 34642212›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Neurokinin B-Expressing Neurons of the Central Extended Amygdala Mediate Inhibitory Synaptic Input onto Melanin-Concentrating Hormone Neuron Subpopulations.

Akie Fujita, Lily Zhong, Monica S Antony, Elizabeth Chamiec-Case, Laura E Mickelsen, Scott E Kanoski, William F Flynn, Alexander C Jackson

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Central Role of Hypothalamic Circuits for Acupuncture's Anti-Parkinsonian Effects.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Akie FujitaDepartments of Physiology and Neurobiology and.ORCID 0000-0003-4797-8543
Lily ZhongDepartments of Physiology and Neurobiology and.
Monica S AntonyDepartments of Physiology and Neurobiology and.
Elizabeth Chamiec-CaseDepartments of Physiology and Neurobiology and.
Laura E MickelsenDepartments of Physiology and Neurobiology and.
Scott E KanoskiHuman & Evolutionary Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089.
William F FlynnThe Jackson Laboratory for Genomic Medicine, Farmington, Connecticut 06032.
Alexander C JacksonDepartments of Physiology and Neurobiology and alexander.jackson@uconn.edu.ORCID 0000-0001-7489-3946
University of Connecticut · USJackson Laboratory · USUniversity of Southern California · US

Funding

Inhibitory Cell Types and Circuits in the Lateral HypothalamusR01MH112739 · NIMH · UNIVERSITY OF CONNECTICUT STORRS · PI Alexander Choi Jackson · 2017 to 2026
$5.1M
Control of feeding behavior by melanin-concentrating hormoneR01DK118402 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Scott Edward Kanoski · 2018 to 2026
$3.2M
Leica TCS SP8 FSU AOBS 405 UV Spectral Confocal MicroscopeS10OD016435 · OD · UNIVERSITY OF CONNECTICUT STORRS · PI NISHIYAMA, AKIKO · 2014 to 2014
$456k
NIDDK NIH HHS R01 DK118402NIH HHS S10 OD016435NIMH NIH HHS R01 MH112739
6 · The paper itself

Abstract

The lateral hypothalamic area (LHA) is a highly conserved brain region critical for maintaining physiological homeostasis and goal-directed behavior. LHA neurons that express melanin-concentrating hormone (MCH) are key regulators of arousal, energy balance, and motivated behavior. However, cellular and functional diversity among LHA

Indexed as

AnimalsCentral Amygdaloid NucleusHypothalamic Area, LateralHypothalamic HormonesMaleMelaninsMiceMice, TransgenicNeural PathwaysNeurokinin BNeuronsPituitary HormonesHypothalamic Hormonesmelanin-concentrating hormoneMelaninsNeurokinin BPituitary Hormonesbed nucleus of the stria terminaliscentral nucleus of the amygdalalateral hypothalamic areamelanin-concentrating hormoneneurokinin-3 receptorneurokinin B

Identifiers

PMID34642212
PMCPMC8612477
OpenAlexW3205472224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.