Evidence map›Paper›PMID 34642211›Full record

ReviewMolecular cancer therapeutics2021

Kristina Mardinian, Jacob J Adashek, Gregory P Botta, Shumei Kato, Razelle Kurzrock

Open access · bronzeAbstract readReview
In one paragraph

Review in Molecular cancer therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 166 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. RNA-Seq Profiling Reveals Transcriptional Changes in Phosphorylation-Site Mutants of Brg1.Genes to cells : devoted to molecular & cellular mechanisms · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. SMARCA4-Directed Treatment in Oncology Clinical Trials: A Review.Journal of immunotherapy and precision oncology · 2026
    Review
  16. Article
  17. Article
  18. Article
  19. An update on the role of SMARCA4 deficiency in gynecological neoplasms: how and where.Virchows Archiv : an international journal of pathology · 2026
    Review
  20. Article

68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Kristina MardinianCenter for Personalized Cancer Therapy, University of California San Diego, Moores Cancer Center, La Jolla, California.
Jacob J AdashekDepartment of Internal Medicine, University of South Florida, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida. jadashek@westernu.edu teoam2011@gmail.com.ORCID 0000-0003-4272-312X
Gregory P BottaCenter for Personalized Cancer Therapy, University of California San Diego, Moores Cancer Center, La Jolla, California.
Shumei KatoCenter for Personalized Cancer Therapy, University of California San Diego, Moores Cancer Center, La Jolla, California.
Razelle KurzrockCenter for Personalized Cancer Therapy, University of California San Diego, Moores Cancer Center, La Jolla, California. jadashek@westernu.edu teoam2011@gmail.com.ORCID 0000-0003-4110-1214
Center for Personalized Cancer Treatment · NLMoffitt Cancer Center · US

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jesse Nodora · 1985 to 2026
$124.9M
NCI NIH HHS P30 CA023100
6 · The paper itself

Abstract

The SWI/SNF chromatin remodeling complex, via nucleosome topology modulation, regulates transcription. The SMARCA4 (BRG1) subunit codes for the ATPase energy engine of the SWI/SNF complex.

Indexed as

AdolescentAdultChildChromatinDNA HelicasesFemaleHumansMiddle AgedNeoplasmsNuclear ProteinsTranscription FactorsYoung AdultChromatinDNA HelicasesNuclear ProteinsSMARCA4 protein, humanTranscription Factors

Identifiers

PMID34642211
PMCPMC8643328
OpenAlexW3206988982

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.