Evidence map›Paper›PMID 34641972›Full record

ArticleParasites & vectors2021

Bartonella spp. seroprevalence in tick-exposed Swedish patients with persistent symptoms.

Marie Edvinsson, Camilla Norlander, Kenneth Nilsson, Andreas Mårtensson, Elisabet Skoog, Björn Olsen

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Distribution ofInternational journal for parasitology. Parasites and wildlife · 2026
    Article
  3. Prevalence and Molecular Characterization ofAnimals : an open access journal from MDPI · 2025
    Article
  4. Molecular Survey ofPathogens (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marie EdvinssonDepartment of Medical Sciences, Section of Infectious Diseases, Uppsala University, Uppsala, Sweden. marie.edvinsson@medsci.uu.se.ORCID http://orcid.org/0000-0003-2845-9190
Camilla NorlanderDepartment of Medical Sciences, Section of Infectious Diseases, Uppsala University, Uppsala, Sweden.
Kenneth NilssonDepartment of Medical Sciences, Section of Infectious Diseases, Uppsala University, Uppsala, Sweden.
Andreas MårtenssonDepartment of Women's and Children's Health, International Maternal and Child Health (IMCH), Uppsala University, Uppsala, Sweden.
Elisabet SkoogDepartment of Medical Sciences, Section of Infectious Diseases, Uppsala University, Uppsala, Sweden.
Björn OlsenDepartment of Medical Sciences, Section of Infectious Diseases, Uppsala University, Uppsala, Sweden.
Uppsala University · SE

Funding

Landstinget i Uppsala län 1040311Landstinget i Uppsala län 41403Landstinget i Uppsala län 42309
6 · The paper itself

Abstract

backgroundBartonella spp. are emerging pathogens transmitted by arthropod vectors, possibly including ticks. We have investigated signs of bartonellosis in Swedish patients with presumed tick-bite exposure and symptom duration of at least 6 months.

methodsSerological testing for Bartonella henselae and Bartonella quintana was performed in 224 patients. Symptoms, tick exposure, evidence of co-infection and previous treatments were evaluated. Seropositive patients were compared to a matched group (twofold larger and negative serology) from the same study cohort.

resultsSeroprevalence was 7% for B. henselae and 1% for B. quintana, with one patient testing positive to both agents. Tick bites were reported by 63% of the patients in the seropositive group and 88% in the seronegative group and presumed tick exposure was more common in the seronegative group. Animal contact was equally common in both groups, along with reported symptoms. The most common symptoms were fatigue, muscular symptoms, arthralgia and cognitive symptoms. Exposure to co-infections was evenly distributed in the seropositive and seronegative groups.

conclusionsAntibodies to Bartonella were more common in this cohort of patients than in cohorts of healthy Swedish blood donors in previous studies but lower than those in blood donors from southern Europe. Positive Bartonella serology was not linked to any specific symptom, nor to (suspected) tick-bite exposure.

Indexed as

AdultAgedAnimalsAntibodies, BacterialBartonellaBartonella InfectionsFemaleHumansMaleMiddle AgedSeroepidemiologic StudiesSerologic TestsSwedenTick BitesTick-Borne DiseasesTicksAntibodies, BacterialBartonellaTicksVector-borne disease

Identifiers

PMID34641972
PMCPMC8507314
OpenAlexW3205647025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.