Evidence map›Paper›PMID 34641892›Full record

Observational studyAIDS research and therapy2021

HIV Care Coordination promotes care re-engagement and viral suppression among people who have been out of HIV medical care: an observational effectiveness study using a surveillance-based contemporaneous comparison group.

Mary K Irvine, McKaylee M Robertson, Denis Nash, Sarah G Kulkarni, Sarah L Braunstein, Bruce Levin

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in AIDS research and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mary K Irvine *Bureau of Hepatitis, HIV and Sexually Transmitted Infections , New York City Department of Health and Mental Hygiene, 42-09 28th Street, CN 21-74, Queens, New York, NY, 11101-4132, USA. mirvine@health.nyc.gov.ORCID 0000-0003-1852-7559
McKaylee M Robertson *Institute for Implementation Science in Population Health (ISPH), Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, NY, USA.
Denis NashInstitute for Implementation Science in Population Health (ISPH), Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, NY, USA.
Sarah G KulkarniInstitute for Implementation Science in Population Health (ISPH), Graduate School of Public Health and Health Policy, City University of New York (CUNY), New York, NY, USA.
Sarah L BraunsteinBureau of Hepatitis, HIV and Sexually Transmitted Infections , New York City Department of Health and Mental Hygiene, 42-09 28th Street, CN 21-74, Queens, New York, NY, 11101-4132, USA.
Bruce LevinDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA.
City University of New York · USNew York City Department of Health and Mental Hygiene · USColumbia University · US

Funding

"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8M
HIV care coordination: comparative effectiveness, outcome determinants and costsR01MH101028 · NIMH · HUNTER COLLEGE · PI IRVINE, MARY KATHRYN, NASH, DENIS · 2013 to 2017
$3.1M
PROMISE - Program Refinements to Optimize Model Impact and Scalability based on EvidenceR01MH117793 · NIMH · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · PI IRVINE, MARY KATHRYN, NASH, DENIS · 2018 to 2022
$2.8M
HRSA HHS HA89HA00015NIAID NIH HHS U01 AI096299NIMH NIH HHS R01 MH101028NIMH NIH HHS R01 MH117793
6 · The paper itself

Abstract

backgroundMedical care re-engagement is critical to suppressing viral load and preventing HIV transmission, morbidity and mortality, yet few rigorous intervention studies address this outcome. We assessed the effectiveness of a Ryan White Part A-funded HIV Care Coordination Program relative to 'usual care,' for short-term care re-engagement and viral suppression among people without recent HIV medical care.

methodsThe Care Coordination Program was launched in 2009 at 28 hospitals, health centers, and community-based organizations in New York City. Designed for people with HIV (PWH) experiencing or at risk for poor HIV outcomes, the Care Coordination Program provides long-term, comprehensive medical case management utilizing interdisciplinary teams, structured health education and patient navigation. The intervention was implemented as a safety-net services program, without a designated comparison group. To evaluate it retrospectively, we created an observational, matched cohort of clients and controls. Using the HIV surveillance registry, we identified individuals meeting program eligibility criteria from December 1, 2009 to March 31, 2013 and excluded those dying prior to 12 months of follow-up. We then matched clients to controls on baseline status (lacking evidence of viral suppression, consistently suppressed, inconsistently suppressed, or newly diagnosed in the past 12 months), start of follow-up and propensity score. For this analysis, we limited to those out of care at baseline (defined as having no viral load test in the 12 months pre-enrollment) and still residing within jurisdiction (defined as having a viral load or CD4 test reported to local surveillance and dated within the 12-month follow-up period). Using a GEE model with binary error distribution and logit link, we compared odds of care re-engagement (defined as having ≥ 2 laboratory events ≥ 90 days apart) and viral suppression (defined as having HIV RNA ≤ 200 copies/mL on the most recent viral load test) at 12-month follow-up.

resultsAmong 326 individuals out of care at baseline, 87.2% of clients and 48.2% of controls achieved care re-engagement (Odds Ratio: 4.53; 95%CI 2.66, 7.71); 58.3% of clients and 49.3% of controls achieved viral suppression (Odds Ratio: 2.05; 95%CI 1.30, 3.23).

conclusionsHIV Care Coordination shows evidence of effectiveness for care and treatment re-engagement.

Indexed as

HIV InfectionsCohort StudiesContinuity of Patient CareHumansRetrospective StudiesViral LoadCare re-engagementCase managementCohort studiesHIV care continuumHIV surveillanceNorth AmericaPublic healthRyan WhiteViral suppression

Identifiers

PMID34641892
PMCPMC8513355
OpenAlexW3207427423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.