Observational studyBMC geriatrics2021
Sarcopenia index based on serum creatinine and cystatin C predicts the risk of postoperative complications following hip fracture surgery in older adults.
Observational study in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 5 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 5 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Prognostic assessment of sarcopenia in patients with fractures: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- Sarcopenia and risk of postoperative pneumonia: a systematic review and meta-analysis.The journal of nutrition, health & aging · 2025Pooled it
- Impact of frailty on postoperative complications in older adults after hip fracture: a systematic review of observational studies.Frontiers in medicine · 2025Pooled it
- What are Risk Factors of Postoperative Pneumonia in Geriatric Individuals after Hip Fracture Surgery: A Systematic Review and Meta-Analysis.Orthopaedic surgery · 2023Pooled it
- Effects of Frailty on Outcomes Following Surgery Among Patients With Hip Fractures: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2022Pooled it
- Does pre-operative metabolic and nutritional assessment have greater association with perioperative complications than frailty following surgical intervention for proximal humerus fractures?JSES reviews, reports, and techniques · 2026Article
- Development and Validation of a Robust Prediction Model for Postoperative Pneumonia in Elderly Patients with Hip Fracture: Integrating Frailty, Nutrition, and Comprehensive Risk Assessment.Risk management and healthcare policy · 2026Article
- Sarcopenia index is a superior prognostic marker to creatinine-cystatin C ratio in older adults with hip fracture.Journal of orthopaedic surgery and research · 2025Article
- Role of cystatin C-based sarcopenia index in predicting postoperative infectious complications after major urologic cancer surgery.International journal of clinical oncology · 2025Article
- Effect of sarcopenia combined with Metabolic Syndrome (MS) on the prognosis of intertrochanteric fractures: a retrospective clinical study.BMC musculoskeletal disorders · 2025Article
- Utilizing machine learning approaches to investigate the relationship between cystatin C and serious complications in esophageal cancer patients after esophagectomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Observational
- Serum cystatin C as a biomarker to predict all-cause mortality in geriatrics hip fracture.Heliyon · 2024Article
- Construction and validation of a predictive model for the risk of prolonged preoperative waiting time in patients with intertrochanteric fractures.Frontiers in medicine · 2024Article
- The use of angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers may relate to the survival and walking ability in geriatric patients with hip fractures: a 1-year follow-up study.BMC musculoskeletal disorders · 2023Article
- Sarcopenia index as a predictor of clinical outcomes among older adult patients with acute exacerbation of chronic obstructive pulmonary disease: a cross-sectional study.BMC geriatrics · 2023Article
- Incidence, Causes, and Risk Factors of Unplanned Readmissions in Elderly Patients Undergoing Hip Fracture Surgery: An Observational Study.Clinical interventions in aging · 2023Observational
- Clinical muscle mass-related biomarkers that predict mortality in older patients with community-acquired pneumonia.BMC geriatrics · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the utility of the preoperative Sarcopenia index (SI) as a predictive marker of the risk of postoperative complications following hip fracture surgery in older adults. STUDY
designThis observational study enrolled older adults with hip fracture who were hospitalized in the Department of Orthopedics of West China Hospital, Sichuan University, from December 7, 2010 - June 14, 2017, and who underwent hip fracture surgery. PRIMARY OUTCOME AND MEASURES: Clinical data were collected from medical records and serum creatinine and cystatin C were measured before surgery. Outcomes included postoperative complications such as pneumonia, urinary tract infection, respiratory failure, heart failure, and non-grade A healing. Binary logistic regression analyses were used to analyze association between SI and postoperative complications.
resultsA total of 897 patients aged 60 years and over were enrolled in this study (age range: 60 - 100 years), of whom 306(34.1%)were male, and 591(65.9%)were female. Postoperative complications included pneumonia (12%), urinary tract infections (1.8%), respiratory failure (1.5%), heart failure (1.6%), and non-A- grade healing (3.6%). In the patient group that received joint replacements, the incidence of pneumonia was negatively associated with SI values. After adjusting for potential confounding factors, binary logistic regression analyses showed that a higher SI was independently associated with a lower risk of pneumonia after joint replacement surgery (OR:0.39, 95% CI:0.18-0.89, P<0.05). However, we did not find statistically significant association between SI and the risk of postoperative complications other than pneumonia among patients with two types of hip fracture surgery.
conclusionThe SI based on serum creatinine and cystatin C can predict pneumonia rather than other postoperative complications among older patients with hip fracture after joint replacement surgery.
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