ReviewMolecules (Basel, Switzerland)2021
Proceedings of Chemistry, Pharmacology, Pharmacokinetics and Synthesis of Biflavonoids.
Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 66 citations in OpenAlex.
- Phenolic compounds fromResearch in pharmaceutical sciences · 2026Article
- Patterns of Biflavonoid Accumulation in Ginkgo (Plants (Basel, Switzerland) · 2026Article
- Pistaciaphenols A-E: novel chalcone-based biflavonoids from the branches of Pistacia chinensis.Journal of natural medicines · 2026Article
- Synthetic Strategies and Biological Diversity of Biflavonoids: Current Status and Perspective.Molecules (Basel, Switzerland) · 2026Review
- Amentoflavone and cancer: mechanistic insights and translational perspectives.Frontiers in oncology · 2026Review
- Dimerized Power: The Antimicrobial and Antiviral Promise of Biflavonoids.Biomolecules · 2025Review
- Review
- Gymnosperm-specific CYP90Js enable biflavonoid biosynthesis and microbial production of amentoflavone.Nature communications · 2025Article
- Food Grade Synthesis of Hetero-Coupled Biflavones and 3D-Quantitative Structure-Activity Relationship (QSAR) Modeling of Antioxidant Activity.Antioxidants (Basel, Switzerland) · 2025Article
- Procyanidins as potential anticancer agents: mechanisms of action, bioavailability challenges and therapeutic opportunities.Medical oncology (Northwood, London, England) · 2025Review
- Biflavonoid Methylchamaejasmin and Khaya grandifoliola Extract Inhibit NLRP3 Inflammasome in THP-1 Cell Model of Neuroinflammation.Molecular neurobiology · 2025Article
- Beyond Essential Oils: Diterpenes, Lignans, and Biflavonoids fromPlants (Basel, Switzerland) · 2024Review
- Seasonal Variation of Polyphenols and Pigments in Ginkgo (Plants (Basel, Switzerland) · 2024Article
- 3'-8″- Biflavones: A Review of Their Structural Diversity, Natural Occurrence, Role in Plants, Extraction and Identification.Molecules (Basel, Switzerland) · 2024Review
- Biflavonoids: Preliminary Reports on Their Role in Prostate and Breast Cancer Therapy.Pharmaceuticals (Basel, Switzerland) · 2024Review
- A Comparative Analysis of Radical Scavenging, Antifungal and Enzyme Inhibition Activity of 3'-8″-Biflavones and Their Monomeric Subunits.Antioxidants (Basel, Switzerland) · 2023Article
- Spiro-Flavonoids in Nature: A Critical Review of Structural Diversity and Bioactivity.Molecules (Basel, Switzerland) · 2023Review
- Advances in the Anti-Tumor Activity of Biflavonoids inInternational journal of molecular sciences · 2023Review
- Neuroprotective Potential of Biflavone Ginkgetin: A Review.Life (Basel, Switzerland) · 2023Review
- Metabolome profile variations in common bean (Frontiers in genetics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biflavonoids, composed of two monoflavonoid residues, occur naturally in angiosperms, bryophytes, ferns, and gymnosperms. More than 592 biflavonoids have been structurally elucidated, and they can be classified into two groups of C-C and C-linear fragments-C, based on whether the linker between the two residues contains an atom. As the linker can be established on two arbitrary rings from different residues, the C-C type contains various subtypes, as does the C-linear fragment-C type. Biflavonoids have a wide range of pharmacological activities, including anti-inflammatory, antioxidant, antibacterial, antiviral, antidiabetic, antitumor, and cytotoxic properties, and they can be applied in Alzheimer's disease and Parkinson's disease. This review mainly summarizes the distribution and chemistry of biflavonoids; additionally, their bioactivities, pharmacokinetics, and synthesis are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.