Evidence map›Paper›PMID 34641629›Full record

ArticleMolecules (Basel, Switzerland)2021

Cudraxanthone D Ameliorates Psoriasis-like Skin Inflammation in an Imiquimod-Induced Mouse Model via Inhibiting the Inflammatory Signaling Pathways.

Namkyung Kim, Soyoung Lee, Jinjoo Kang, Young-Ae Choi, Yong Hyun Jang, Gil-Saeng Jeong, Sang-Hyun Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Namkyung KimDepartment of Pharmacology, Cell & Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Soyoung LeeImmunoregulatory Materials Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 28116, Korea.
Jinjoo KangDepartment of Pharmacology, Cell & Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Young-Ae ChoiDepartment of Pharmacology, Cell & Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Yong Hyun JangDepartments of Dermatology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Gil-Saeng JeongCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Sang-Hyun KimDepartment of Pharmacology, Cell & Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Kyungpook National University · KRChungnam National University · KRKorea Research Institute of Bioscience and Biotechnology · KR

Funding

National Research Foundation of Korea 2017M3A9G8083382National Research Foundation of Korea 2019M3A9H1103690National Research Foundation of Korea 2019R1C1C1005172,National Research Foundation of Korea 2020M3A9D3038894National Research Foundation of Korea 2020R1A2C1010962
6 · The paper itself

Abstract

Psoriasis is a chronic inflammatory skin disease accompanied by excessive keratinocyte proliferation. Corticosteroids, vitamin D3 analogs, and calcineurin inhibitors, which are used to treat psoriasis, have diverse adverse effects, whereas natural products are popular due to their high efficiency and relatively low toxicity. The roots of the

Indexed as

Administration, OralAnimalsAnti-Inflammatory AgentsCell LineDisease Models, AnimalFemaleHumansImiquimodInterferon-gammaKeratinocytesMiceMice, Inbred BALB CMice, Inbred C57BLMoraceaeNF-kappa BPlant ExtractsAnti-Inflammatory AgentsImiquimodInterferon-gammaNF-kappa BPlant ExtractsTumor Necrosis Factor-alphaXanthonesCudrania tricuspidata Bureaucudraxanthone Dimiquimodkeratinocytespsoriasis

Identifiers

PMID34641629
PMCPMC8512696
OpenAlexW3204936172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.