Evidence map›Paper›PMID 34641610›Full record

ArticleMolecules (Basel, Switzerland)2021

New 4-Aminoproline-Based Small Molecule Cyclopeptidomimetics as Potential Modulators of α

Andrea Sartori, Kelly Bugatti, Elisabetta Portioli, Monica Baiula, Irene Casamassima, Agostino Bruno, Francesca Bianchini, Claudio Curti, Franca Zanardi, Lucia Battistini

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Design and Pharmacological Characterization of αJournal of medicinal chemistry · 2023
    Article
  3. Women in Bioorganic Chemistry.Molecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Andrea SartoriDepartment of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.ORCID 0000-0002-9688-6760
Kelly BugattiDepartment of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
Elisabetta PortioliDepartment of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
Monica BaiulaDepartment of Pharmacy and Biotechnology, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.
Irene CasamassimaDepartment of Pharmacy and Biotechnology, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.
Agostino BrunoDepartment of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
Francesca BianchiniDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Viale G.B. Morgagni 50, 50134 Firenze, Italy.ORCID 0000-0002-5839-4298
Claudio CurtiDepartment of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.ORCID 0000-0002-6117-1503
Franca ZanardiDepartment of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.ORCID 0000-0001-7451-781X
Lucia BattistiniDepartment of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.ORCID 0000-0002-5341-5547
University of Parma · ITUniversity of Bologna · ITUniversity of Florence · IT

Funding

Università degli Studi di Parma BATTISTINI_L_FIL, ZNRFNC_RICERCA_IST
6 · The paper itself

Abstract

Integrin α

Indexed as

Cell AdhesionHumansIntegrin alpha4beta1Jurkat CellsLigandsModels, MolecularOligopeptidesPeptides, CyclicPeptidomimeticsProlineProtein BindingProtein ConformationaminoprolineIntegrin alpha4beta1leucyl-aspartyl-valineLigandsOligopeptidesPeptides, CyclicPeptidomimeticsProlineaminoproline scaffoldintegrin targetingleukocyte integrinsligand designpeptidomimetic synthesis

Identifiers

PMID34641610
PMCPMC8512764
OpenAlexW3206896251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.