Evidence map›Paper›PMID 34641545›Full record

ArticleMolecules (Basel, Switzerland)2021

Olive Pomace Phenolic Compounds Stability and Safety Evaluation: From Raw Material to Future Ophthalmic Applications.

Nikolaos Katsinas, Amalia Enríquez-de-Salamanca, Andreia Bento da Silva, Maria Rosário Bronze, Soraya Rodríguez-Rojo

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Nikolaos KatsinasResearch Institute on Bioeconomy (BioEcoUVa), High Pressure Processes Group, School of Engineering, University of Valladolid (UVa), Dr. Mergelina Street, 47011 Valladolid, Spain.ORCID 0000-0001-7776-8948
Amalia Enríquez-de-SalamancaInstitute of Applied Ophthalmobiology (IOBA), Campus Miguel Delibes, University of Valladolid (UVa), Paseo de Belén 17, 47011 Valladolid, Spain.ORCID 0000-0003-1274-7796
Andreia Bento da SilvaInstituto de Investigação do Medicamento (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa (FFULisboa), Av. Prof. Gama Pinto, 1649-019 Lisbon, Portugal.ORCID 0000-0002-3047-0586
Maria Rosário BronzeInstituto de Investigação do Medicamento (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa (FFULisboa), Av. Prof. Gama Pinto, 1649-019 Lisbon, Portugal.ORCID 0000-0001-5016-4634
Soraya Rodríguez-RojoResearch Institute on Bioeconomy (BioEcoUVa), High Pressure Processes Group, School of Engineering, University of Valladolid (UVa), Dr. Mergelina Street, 47011 Valladolid, Spain.ORCID 0000-0002-9054-1462
Universidad de Valladolid · ESUniversity of Lisbon · PT

Funding

European Union's Horizon 2020 research and innovation program IT-DED3 (H2020-MSCA-ITN-2017) grant agreement No. 765608.Universidad de Valladolid Post-doctoral grant S.R.R.
6 · The paper itself

Abstract

Nowadays, increasing interest in olive pomace (OP) valorization aims to improve olive's industry sustainability. Interestingly, several studies propose a high-value application for OP extracts containing its main phenolic compounds, hydroxytyrosol and oleuropein, as therapy for ocular surface diseases. In this work, the stability and accessibility of OP total phenolic and flavonoid content, main representative compounds, and antioxidant activity were assessed under different pretreatment conditions. Among them, lyophilization and supercritical CO

Indexed as

AldehydesCell LineChromatography, High Pressure LiquidComet AssayCorneaDrug Evaluation, PreclinicalDrug StabilityHumansOleaOphthalmic SolutionsPhenolsPhenylethyl AlcoholPlant ExtractsTandem Mass Spectrometry3,4-dihydroxyphenylethanolAldehydesoleaceinOphthalmic SolutionsPhenolsPhenylethyl AlcoholPlant Extractsgenotoxicity assayhydroxytyrosololeuropeinolive pomacephenolic extractsstorage stability

Identifiers

PMID34641545
PMCPMC8512844
OpenAlexW3202855188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.