Evidence map›Paper›PMID 34641542›Full record

ReviewMolecules (Basel, Switzerland)2021

Potential Role of Natural Products to Combat Radiotherapy and Their Future Perspectives.

Rokeya Akter, Agnieszka Najda, Md Habibur Rahman, Muddaser Shah, Sylwia Wesołowska, Syed Shams Ul Hassan, Sidra Mubin, Parveen Bibi, Saeeda Saeeda

RetractedAbstract readReviewRetracted Publication
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Rokeya AkterDepartment of Pharmacy, Jagannath University, Dhaka 1100, Bangladesh.
Agnieszka NajdaDepartment of Vegetable and Herbal Crops, University of Life Sciences in Lublin, 50A Doświadczalna Street, 20-280 Lublin, Poland.ORCID 0000-0002-1185-8884
Md Habibur RahmanDepartment of Global Medical Science, Wonju College of Medicine, Yonsei University, Gangwon-do, Wonju 26426, Korea.ORCID 0000-0001-6099-5693
Muddaser ShahDepartment of Botany, Abdul Wali Khan University Mardan, Mardan 23200, Pakistan.ORCID 0000-0001-8839-4419
Sylwia WesołowskaInstitute of Soil Science and Environment Shaping, University of Life Sciences in Lublin, 7 Leszczyńskiego Street, 20-069 Lublin, Poland.
Syed Shams Ul HassanShanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmacy, Shanghai JiaoTong University, Shanghai 200240, China.ORCID 0000-0001-5188-6540
Sidra MubinDepartment of Botany, Hazara University Mansehra, Mansehra 21310, Pakistan.ORCID 0000-0001-6042-4209
Parveen BibiDepartment of Botany, Abdul Wali Khan University Mardan, Mardan 23200, Pakistan.
Saeeda SaeedaDepartment of Botany, Abdul Wali Khan University Mardan, Mardan 23200, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is the second leading cause of death in the world. Chemotherapy and radiotherapy (RT) are the common cancer treatments. In addition to these limitations, the development of adverse effects from chemotherapy and RT reduces the quality of life for cancer patients. Cellular radiosensitivity, or the ability to resist and overcome cell damage caused by ionizing radiation (IR), is directly related to cancer cells' response to RT. Therefore, radiobiological research is emphasizing chemical compounds 'radiosensitization of cancer cells so that they are more reactive in the IR spectrum. Recent years researchers have seen an increase in interest in natural products that have antitumor effects with minimal side effects. Natural products, on the other hand, are easy to recover and therefore less expensive. There have been several scientific studies done based on these compounds that have tested their ability in vitro and in vivo to induce tumor radiosensitization. The role of natural products in RT, as well as their usefulness and potential applications, is the goal of this current review.

Indexed as

BerberineBiological ProductsCurcuminEmodinGenisteinHumansNeoplasmsPentacyclic TriterpenesRadiation-Protective AgentsRadiation-Sensitizing AgentsRadiotherapyResveratrolSesquiterpenesTriterpenesUrsolic AcidVitamin DBerberineBiological ProductscelastrolCurcuminEmodinGenisteinPentacyclic TriterpenesRadiation-Protective AgentsRadiation-Sensitizing AgentsResveratrolSesquiterpenesTriterpenesUrsolic AcidVitamin Dwithaferin AWithanolideszerumbonecancerchemotherapynatural productsradiotherapytherapeutic

Identifiers

PMID34641542
PMCPMC8512367

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.