Evidence map›Paper›PMID 34641520›Full record

ArticleMolecules (Basel, Switzerland)2021

Cordycepin Sensitizes Cholangiocarcinoma Cells to Be Killed by Natural Killer-92 (NK-92) Cells.

Suthida Panwong, Methi Wathikthinnakon, Thida Kaewkod, Nunghathai Sawasdee, Yingmanee Tragoolpua, Pa-Thai Yenchitsomanus, Aussara Panya

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  8. The role and mechanisms of cordycepin in inhibiting cancer cells.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Suthida PanwongMaster of Science Program in Applied Microbiology (International Program), Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
Methi WathikthinnakonDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-3949-9887
Thida KaewkodDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
Nunghathai SawasdeeDivision of Molecular Medicine, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Yingmanee TragoolpuaDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
Pa-Thai YenchitsomanusDivision of Molecular Medicine, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.ORCID 0000-0001-9779-5927
Aussara PanyaDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
Chiang Mai University · THSiriraj Hospital · TH

Funding

Center of Excellence on Medical Biotechnology (CEMB), The S&T Postgraduate Education and Research Development Office (PERDO), The Commission on Higher Education (CHE), Thailand grant no. R000018103
6 · The paper itself

Abstract

Immunotherapy harnessing immune functions is a promising strategy for cancer treatment. Tumor sensitization is one approach to enhance tumor cell susceptibility to immune cell cytotoxicity that can be used in combination with immunotherapy to achieve therapeutic efficiency. Cordycepin, a bioactive compound that can be extracted from some

Indexed as

Antineoplastic Agents, PhytogenicBile Duct NeoplasmsCell LineCell Line, TumorCell ProliferationCholangiocarcinomaCordycepsDeoxyadenosinesfas ReceptorGene Expression Regulation, NeoplasticHistocompatibility Antigens Class IHumansKiller Cells, NaturalPlant ExtractsReceptors, TNF-Related Apoptosis-Inducing LigandAntineoplastic Agents, PhytogeniccordycepinDeoxyadenosinesFAS protein, humanfas ReceptorHistocompatibility Antigens Class IMICB antigenPlant ExtractsReceptors, TNF-Related Apoptosis-Inducing LigandTNFRSF10B protein, humancancer treatmentcholangiocarcinomacordycepinimmunomodulationNK cell-based immunotherapysensitization

Identifiers

PMID34641520
PMCPMC8512070
OpenAlexW3203894077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.