Evidence map›Paper›PMID 34641486›Full record

ArticleMolecules (Basel, Switzerland)2021

Modulation of the NOTCH1 Pathway by LUNATIC FRINGE Is Dominant over That of MANIC or RADICAL FRINGE.

Florian Pennarubia, Alison V Nairn, Megumi Takeuchi, Kelley W Moremen, Robert S Haltiwanger

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. IncreasedInternational journal of molecular sciences · 2024
    Article
  6. Article
  7. Article
  8. MFNG is an independent prognostic marker for osteosarcoma.European journal of medical research · 2023
    Article
  9. Special Issue: New Insights into Protein Glycosylation.Molecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Florian PennarubiaComplex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.
Alison V NairnComplex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.
Megumi TakeuchiComplex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.
Kelley W MoremenComplex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.ORCID 0000-0003-1768-582X
Robert S HaltiwangerComplex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.ORCID 0000-0001-7439-9577
University of Georgia · US

Funding

TR&D1: Stem Cell and Induced Pluripotent Stem Cell Resources (Pages 116-134)P41GM103490 · NIGMS · UNIVERSITY OF GEORGIA · PI PIERCE, J. MICHAEL · 2012 to 2018
$13.7M
O-Glycosylation of Epidermal Growth Factor-like MotifsR01GM061126 · NIGMS · UNIVERSITY OF GEORGIA · PI HALTIWANGER, ROBERT S. · 2001 to 2021
$9.1M
NIGMS NIH HHS P41GM103490NIGMS NIH HHS R01 GM061126NIGMS NIH HHS R01GM061126
6 · The paper itself

Abstract

Fringes are glycosyltransferases that transfer a GlcNAc to

Indexed as

AnimalsBone NeoplasmsCells, CulturedCHO CellsCricetulusFucoseGlucosyltransferasesGlycosyltransferasesHumansMiceNIH 3T3 CellsOsteosarcomaReceptor, Notch1Signal TransductionFucoseGlucosyltransferasesGlycosyltransferasesLFNG protein, humanMFNG protein, humanNOTCH1 protein, humanReceptor, Notch1RFNG protein, humanEGF-like domainsFringeglycosylationNOTCH1O-fucosylation

Identifiers

PMID34641486
PMCPMC8512825
OpenAlexW3201686141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.