ArticleMolecules (Basel, Switzerland)2021
Lycoperoside H, a Tomato Seed Saponin, Improves Epidermal Dehydration by Increasing Ceramide in the Stratum Corneum and Steroidal Anti-Inflammatory Effect.
Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Effect of Rice (Nutrients · 2022Trial
- Integrated Transcriptome and Metabolome Analysis of Fruit Quality Variation in 'Sweet100' Tomato Across Different Growth Stages.Foods (Basel, Switzerland) · 2026Article
- Hepatoprotective Effect ofSultan Qaboos University medical journal · 2026Article
- Peppermint hydrosol as a novel bio-stimulant promotes growth and antioxidant activity of Solanum lycopersicum L.BMC plant biology · 2025Article
- Phytochemical and Biological Biodiversity of Tomato (Mini reviews in medicinal chemistry · 2025Review
- Comparative Study on Epidermal Moisturizing Effects and Hydration Mechanisms of Rice-Derived Glucosylceramides and Ceramides.International journal of molecular sciences · 2022Article
- Bio-Functional Natural Products in Edible Resources for Human Health and Beauty.Molecules (Basel, Switzerland) · 2022Article
- Tomatoes: An Extensive Review of the Associated Health Impacts of Tomatoes and Factors That Can Affect Their Cultivation.Biology · 2022Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Tomatoes are widely consumed, however, studies on tomato seeds are limited. In this study, we isolated 11 compounds including saponins and flavonol glycosides from tomato seeds and evaluated their effects on epidermal hydration. Among the isolated compounds, tomato seed saponins (10 µM) significantly increased the mRNA expression of proteins related to epidermal hydration, including filaggrin, involucrin, and enzymes for ceramide synthesis, by 1.32- to 1.91-fold compared with the control in HaCaT cells. Tomato seed saponins (10 µM) also decreased transepidermal water loss by 7 to 13 g/m
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Registered trials
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