Evidence map›Paper›PMID 34641387›Full record

ArticleMolecules (Basel, Switzerland)2021

Bioflavonoid-Induced Apoptosis and DNA Damage in Amastigotes and Promastigotes of

Shaila Mehwish, Sanjay Varikuti, Mubarak Ali Khan, Tariq Khan, Imdad Ullah Khan, Abhay Satoskar, Hamed Abdelhamid Elsayed Elserehy, Nazif Ullah

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. TargetingFrontiers in pharmacology · 2024
    Article
  7. Review
  8. Article
  9. Anti-Frontiers in microbiology · 2023
    Article
  10. Therapeutic effect of oral quercetin in hamsters infected withFrontiers in cellular and infection microbiology · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Shaila MehwishDepartment of Biotechnology, Faculty of Chemical and Life Sciences, Abdul Wali Khan University Mardan, Mardan 23200, Pakistan.
Sanjay VarikutiDepartment of Pathology, The Ohio State University Medical Center, Columbus, OH 43210, USA.
Mubarak Ali KhanDepartment of Biotechnology, Faculty of Chemical and Life Sciences, Abdul Wali Khan University Mardan, Mardan 23200, Pakistan.ORCID 0000-0002-7994-4244
Tariq KhanDepartment of Biotechnology, Faculty of Biological Sciences, University of Malakand, Chakdara 18800, Pakistan.ORCID 0000-0002-9194-9240
Imdad Ullah KhanDepartment of Biotechnology, Faculty of Chemical and Life Sciences, Abdul Wali Khan University Mardan, Mardan 23200, Pakistan.ORCID 0000-0001-9586-0246
Abhay SatoskarDepartment of Pathology, The Ohio State University Medical Center, Columbus, OH 43210, USA.
Hamed Abdelhamid Elsayed ElserehyDepartment of Zoology, College of Science, King Saud University, Riyad 11451, Saudi Arabia.
Nazif UllahDepartment of Biotechnology, Faculty of Chemical and Life Sciences, Abdul Wali Khan University Mardan, Mardan 23200, Pakistan.
Abdul Wali Khan University Mardan · PKThe Ohio State University Wexner Medical Center · USKing Saud University · SAUniversity of Malakand · PK

Funding

Higher Education Commision, Pakistan 5192/KPK/NRPU/R&D/HEC/2016
6 · The paper itself

Abstract

Natural products from plants contain many interesting biomolecules. Among them, quercetin (Q), gallic acid (GA), and rutin (R) all have well-reported antileishmanial activity; however, their exact mechanisms of action are still not known. The current study is a step forward towards unveil the possible modes of action of these compounds against

Indexed as

ApoptosisDNA DamageAnimalsAntiprotozoal AgentsFlavonoidsLeishmania donovaniLeishmaniasis, VisceralMacrophagesMiceMice, Inbred BALB CNecrosisAntiprotozoal AgentsFlavonoidsapoptosisDNA damagegallic acidLeishmania donovanileishmaniasisquercetinrutin

Identifiers

PMID34641387
PMCPMC8512304
OpenAlexW3204252478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.