Evidence map›Paper›PMID 34641367›Full record

ReviewMolecules (Basel, Switzerland)2021

Synthesis, Chemical-Physical Characterization, and Biomedical Applications of Functional Gold Nanoparticles: A Review.

Ileana Ielo, Giulia Rando, Fausta Giacobello, Silvia Sfameni, Angela Castellano, Maurilio Galletta, Dario Drommi, Giuseppe Rosace, Maria Rosaria Plutino

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 169 citations in OpenAlex.

  1. Review
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  10. UsingInternational journal of molecular sciences · 2025
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  19. Strain-SpecificInternational journal of nanomedicine · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ileana IeloInstitute for the Study of Nanostructured Materials, ISMN-CNR, Palermo, c/o Department of ChiBioFarAm, University of Messina, Viale F. Stagno d'Alcontres 31, Vill. S. Agata, 98166 Messina, Italy.ORCID 0000-0002-6101-8015
Giulia RandoDepartment of Chemical, Biological, Pharmaceutical and Analytical Sciences (ChiBioFarAm), University of Messina, Viale F. Stagno d'Alcontres 31, Vill. S. Agata, 98166 Messina, Italy.ORCID 0000-0002-6618-4311
Fausta GiacobelloInstitute for the Study of Nanostructured Materials, ISMN-CNR, Palermo, c/o Department of ChiBioFarAm, University of Messina, Viale F. Stagno d'Alcontres 31, Vill. S. Agata, 98166 Messina, Italy.ORCID 0000-0002-5148-1540
Silvia SfameniInstitute for the Study of Nanostructured Materials, ISMN-CNR, Palermo, c/o Department of ChiBioFarAm, University of Messina, Viale F. Stagno d'Alcontres 31, Vill. S. Agata, 98166 Messina, Italy.
Angela CastellanoInstitute for the Study of Nanostructured Materials, ISMN-CNR, Palermo, c/o Department of ChiBioFarAm, University of Messina, Viale F. Stagno d'Alcontres 31, Vill. S. Agata, 98166 Messina, Italy.
Maurilio GallettaDepartment of Chemical, Biological, Pharmaceutical and Analytical Sciences (ChiBioFarAm), University of Messina, Viale F. Stagno d'Alcontres 31, Vill. S. Agata, 98166 Messina, Italy.
Dario DrommiDepartment of Chemical, Biological, Pharmaceutical and Analytical Sciences (ChiBioFarAm), University of Messina, Viale F. Stagno d'Alcontres 31, Vill. S. Agata, 98166 Messina, Italy.
Giuseppe RosaceDepartment of Engineering and Applied Sciences, University of Bergamo, Viale Marconi 5, 24044 Dalmine, Italy.ORCID 0000-0003-0604-4453
Maria Rosaria PlutinoInstitute for the Study of Nanostructured Materials, ISMN-CNR, Palermo, c/o Department of ChiBioFarAm, University of Messina, Viale F. Stagno d'Alcontres 31, Vill. S. Agata, 98166 Messina, Italy.ORCID 0000-0002-5980-2003
University of Messina · ITUniversity of Bergamo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Relevant properties of gold nanoparticles, such as stability and biocompatibility, together with their peculiar optical and electronic behavior, make them excellent candidates for medical and biological applications. This review describes the different approaches to the synthesis, surface modification, and characterization of gold nanoparticles (AuNPs) related to increasing their stability and available features useful for employment as drug delivery systems or in hyperthermia and photothermal therapy. The synthetic methods reported span from the well-known Turkevich synthesis, reduction with NaBH

Indexed as

Drug Delivery SystemsAnimalsGoldHumansMetal NanoparticlesPolymersGoldPolymersdrug deliverygold nanoparticlesnanomaterials synthesisphotothermal activity

Identifiers

PMID34641367
PMCPMC8510367
OpenAlexW3204617115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.