Evidence map›Paper›PMID 34641360›Full record

ArticleMolecules (Basel, Switzerland)2021

Cyanoarylporphyrazines with High Viscosity Sensitivity: A Step towards Dosimetry-Assisted Photodynamic Cancer Treatment.

Irina V Balalaeva, Tatiana A Mishchenko, Victoria D Turubanova, Nina N Peskova, Natalia Y Shilyagina, Vladimir I Plekhanov, Svetlana A Lermontova, Larisa G Klapshina, Maria V Vedunova, Dmitri V Krysko

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Irina V BalalaevaDepartment of Biophysics, Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin ave., 603022 Nizhny Novgorod, Russia.ORCID 0000-0002-3245-3907
Tatiana A MishchenkoDepartment of Neurotechnology, Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin ave., 603022 Nizhny Novgorod, Russia.ORCID 0000-0003-4463-5035
Victoria D TurubanovaDepartment of Neurotechnology, Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin ave., 603022 Nizhny Novgorod, Russia.ORCID 0000-0002-4648-0738
Nina N PeskovaDepartment of Biophysics, Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin ave., 603022 Nizhny Novgorod, Russia.
Natalia Y ShilyaginaDepartment of Biophysics, Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin ave., 603022 Nizhny Novgorod, Russia.
Vladimir I PlekhanovDepartment of Radiophysical Methods in Medicine, Federal Research Center Institute of Applied Physics of the Russian Academy of Sciences, 46 Ul'yanov Street, 603950 Nizhny Novgorod, Russia.ORCID 0000-0003-0233-2052
Svetlana A LermontovaSector of Chromophors for Medicine, G.A. Razuvaev Institute of Organometallic Chemistry of the Russian Academy of Sciences, 49 Tropinin st., 603137 Nizhny Novgorod, Russia.
Larisa G KlapshinaSector of Chromophors for Medicine, G.A. Razuvaev Institute of Organometallic Chemistry of the Russian Academy of Sciences, 49 Tropinin st., 603137 Nizhny Novgorod, Russia.
Maria V VedunovaDepartment of Neurotechnology, Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin ave., 603022 Nizhny Novgorod, Russia.ORCID 0000-0001-9759-6477
Dmitri V KryskoDepartment of Basic and Medical Genetics, Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin ave., 603022 Nizhny Novgorod, Russia.ORCID 0000-0002-9692-2047

Funding

Russian Science Foundation 18-15-00279 https://rscf.ru/en/project/18-15-00279/State assignment of the Ministry of Science and Higher Education of the Russian Federation 0729-2020-0061
6 · The paper itself

Abstract

Despite the significant relevance of photodynamic therapy (PDT) as an efficient strategy for primary and adjuvant anticancer treatment, several challenges compromise its efficiency. In order to develop an "ideal photosensitizer" and the requirements applied to photosensitizers for PDT, there is still a need for new photodynamic agents with improved photophysical and photobiological properties. In this study, we performed a detailed characterization of two tetracyanotetra(aryl)porphyrazine dyes with 4-biphenyl (

Indexed as

AnimalsCarcinoma, Squamous CellGliomaHumansMicePhotochemotherapyPhotosensitizing AgentsPorphyrinsSinglet OxygenTumor Cells, CulturedViscosityPhotosensitizing AgentsPorphyrinsSinglet Oxygencancer treatmentcell deathfluorescent molecular rotorsintracellular viscosityphotodynamic therapyphotosensitizersporphyrazines

Identifiers

PMID34641360
PMCPMC8510116

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.