Evidence map›Paper›PMID 34641328›Full record

ArticleMolecules (Basel, Switzerland)2021

Co-Treatments of Edible Curcumin from Turmeric Rhizomes and Chemotherapeutic Drugs on Cytotoxicity and FLT3 Protein Expression in Leukemic Stem Cells.

Fah Chueahongthong, Singkome Tima, Sawitree Chiampanichayakul, Cory Berkland, Songyot Anuchapreeda

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Curcumin in treatment of hematological cancers: Promises and challenges.Journal of traditional and complementary medicine · 2024
    Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Fah ChueahongthongDivision of Clinical Microscopy, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Singkome TimaDivision of Clinical Microscopy, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-3072-3715
Sawitree ChiampanichayakulDivision of Clinical Microscopy, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-3452-8511
Cory BerklandDepartment of Pharmaceutical Chemistry, School of Pharmacy, University of Kansas, Lawrence, KS 66047, USA.ORCID 0000-0002-9346-938X
Songyot AnuchapreedaDivision of Clinical Microscopy, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-7259-4694
Chiang Mai University · THUniversity of Kansas · US

Funding

Royal Golden Jubilee (RGJ) Ph.D. Programme PHD/0086/2559Thailand Research Fund MRG 6180124Thailand Research Fund RSA6280034
6 · The paper itself

Abstract

This study aims to enhance efficacy and reduce toxicity of the combination treatment of a drug and curcumin (Cur) on leukemic stem cell and leukemic cell lines, including KG-1a and KG-1 (FLT3

Indexed as

Antigens, NeoplasmCell Cycle ProteinsCell Line, TumorCell ProliferationCell SurvivalCurcumaCurcuminCytoskeletal ProteinsDose-Response Relationship, DrugDoxorubicinDrug Synergismfms-Like Tyrosine Kinase 3Gene Expression Regulation, NeoplasticHumansIdarubicinLeukemia, Myeloid, AcuteAntigens, NeoplasmCell Cycle ProteinsCep290 protein, humanCurcuminCytoskeletal ProteinsDoxorubicinFLT3 protein, humanfms-Like Tyrosine Kinase 3Idarubicinchemotherapeutic drugco-treatmentcurcuminFLT-3leukemialeukemic stem cell

Identifiers

PMID34641328
PMCPMC8510311
OpenAlexW3204741789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.