Evidence map›Paper›PMID 34641285›Full record

ArticleMolecules (Basel, Switzerland)2021

Bile-Acid-Appended Triazolyl Aryl Ketones: Design, Synthesis, In Vitro Anticancer Activity and Pharmacokinetics in Rats.

Devesh S Agarwal, Samrat Mazumdar, Kishan S Italiya, Deepak Chitkara, Rajeev Sakhuja

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Devesh S AgarwalDepartment of Chemistry, Birla Institute of Technology and Science, Pilani 333 031, India.
Samrat MazumdarDepartment of Pharmacy, Birla Institute of Technology and Science, Pilani 333 031, India.
Kishan S ItaliyaDepartment of Pharmacy, Birla Institute of Technology and Science, Pilani 333 031, India.
Deepak ChitkaraDepartment of Pharmacy, Birla Institute of Technology and Science, Pilani 333 031, India.
Rajeev SakhujaDepartment of Chemistry, Birla Institute of Technology and Science, Pilani 333 031, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A library of bile-acid-appended triazolyl aryl ketones was synthesized and characterized by detailed spectroscopic techniques such as

Indexed as

AnimalsAntineoplastic AgentsBile Acids and SaltsCell Line, TumorCell ProliferationCell SurvivalDose-Response Relationship, DrugDrug Screening Assays, AntitumorHEK293 CellsHumansKetonesMaleMCF-7 CellsMiceMolecular StructureRatsAntineoplastic AgentsBile Acids and SaltsKetonesanticancerapoptosisbile acidcytotoxicitypharmacokinetic study

Identifiers

PMID34641285
PMCPMC8510344

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.