Evidence map›Paper›PMID 34641243›Full record

ReviewPolymers2021

Applications of Polymeric Composites in Bone Tissue Engineering and Jawbone Regeneration.

Oscar Fraile-Martínez, Cielo García-Montero, Alejandro Coca, Miguel Angel Álvarez-Mon, Jorge Monserrat, Ana M Gómez-Lahoz, Santiago Coca, Melchor Álvarez-Mon, Julio Acero, Julia Bujan and 3 more

Abstract readReview
In one paragraph

Review in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Biomimetic Scaffold of Chitosan fromAdvanced pharmaceutical bulletin · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Oscar Fraile-MartínezDepartment of Medicine and Medical Specialities, University of Alcalá, 28801 Alcalá de Henares, Spain.ORCID 0000-0002-4494-6397
Cielo García-MonteroDepartment of Medicine and Medical Specialities, University of Alcalá, 28801 Alcalá de Henares, Spain.ORCID 0000-0001-6016-7855
Alejandro CocaDepartment of Medicine and Medical Specialities, University of Alcalá, 28801 Alcalá de Henares, Spain.
Miguel Angel Álvarez-MonDepartment of Medicine and Medical Specialities, University of Alcalá, 28801 Alcalá de Henares, Spain.
Jorge MonserratDepartment of Medicine and Medical Specialities, University of Alcalá, 28801 Alcalá de Henares, Spain.ORCID 0000-0003-1775-4645
Ana M Gómez-LahozDepartment of Medicine and Medical Specialities, University of Alcalá, 28801 Alcalá de Henares, Spain.
Santiago CocaDepartment of Medicine and Medical Specialities, University of Alcalá, 28801 Alcalá de Henares, Spain.
Melchor Álvarez-MonDepartment of Medicine and Medical Specialities, University of Alcalá, 28801 Alcalá de Henares, Spain.
Julio AceroDepartment of Surgery, Medical and Social Sciences, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Alcalá de Henares, Spain.
Julia BujanDepartment of Medicine and Medical Specialities, University of Alcalá, 28801 Alcalá de Henares, Spain.ORCID 0000-0003-2419-2476
Natalio García-HonduvillaDepartment of Medicine and Medical Specialities, University of Alcalá, 28801 Alcalá de Henares, Spain.ORCID 0000-0003-0904-6198
Ángel AsúnsoloRamón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.ORCID 0000-0001-7898-4685
Miguel A OrtegaDepartment of Medicine and Medical Specialities, University of Alcalá, 28801 Alcalá de Henares, Spain.ORCID 0000-0003-2588-1708

Funding

METHADONE TREATMENT: A STUDY OF A COUNTY POLICY CHANGER01DA003804 · NIDA · SCIENTIFIC ANALYSIS CORPORATION · PI ROSENBAUM, MARSHA · 1985 to 1989
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Comunidad de Madrid B2017/BMD3804
6 · The paper itself

Abstract

Polymer-based composites are a group of biomaterials that exert synergic and combined activity. There are multiple reported uses of these composites in multiple biomedical areas, such as drug carriers, in wound dressings, and, more prominently, in tissue engineering and regenerative medicine. Bone grafting is a promising field in the use of polymeric composites, as this is the second most frequently transplanted organ in the United States. Advances in novel biomaterials, such as polymeric composites, will undoubtedly be of great aid in bone tissue engineering and regeneration. In this paper, a general view of bone structure and polymeric composites will be given, discussing the potential role of these components in bone tissue. Moreover, the most relevant jawbone and maxillofacial applications of polymeric composites will be revised in this article, collecting the main knowledge about this topic and emphasizing the need of further clinical studies in humans.

Indexed as

bone tissue engineeringhydroxyapatite/collagenjawbonepolymeric compositesregenerative medicine

Identifiers

PMID34641243
PMCPMC8512420

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.