Evidence map›Paper›PMID 34641117›Full record

ArticlePolymers2021

Synergies of Human Umbilical Vein Endothelial Cell-Laden Calcium Silicate-Activated Gelatin Methacrylate for Accelerating 3D Human Dental Pulp Stem Cell Differentiation for Endodontic Regeneration.

Wei-Yun Lai, Tzu-Hsin Lee, Jian-Xun Chen, Hooi-Yee Ng, Tsui-Hsien Huang, Ming-You Shie

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Wei-Yun LaiSchool of Dentistry, Chung Shan Medical University, Taichung 406040, Taiwan.
Tzu-Hsin LeeDepartment of Orthodontics, Changhua Christian Hospital, Changhua 500, Taiwan.
Jian-Xun ChenSchool of Medicine, China Medical University, Taichung 40447, Taiwan.
Hooi-Yee NgSchool of Medicine, China Medical University, Taichung 40447, Taiwan.
Tsui-Hsien HuangSchool of Dentistry, Chung Shan Medical University, Taichung 406040, Taiwan.
Ming-You Shiex-Dimension Center for Medical Research and Translation, China Medical University Hospital, Taichung 40447, Taiwan.ORCID 0000-0002-0650-4344
China Medical University · TWAsia University · TWChanghua Christian Hospital · TWChung Shan Medical University · TWChung Shan Medical University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the Centers for Disease Control and Prevention, tooth caries is a common problem affecting 9 out of every 10 adults worldwide. Dentin regeneration has since become one of the pressing issues in dentistry with tissue engineering emerging as a potential solution for enhancing dentin regeneration. In this study, we fabricated cell blocks with human dental pulp stem cells (hDPSCs)-laden alginate/fish gelatin hydrogels (Alg/FGel) at the center of the cell block and human umbilical vascular endothelial cells (HUVEC)-laden Si ion-infused fish gelatin methacrylate (FGelMa) at the periphery of the cell block.

Indexed as

calcium silicatedental pulp stem cellgelatin methacryloylhuman umbilical vein endothelial cellodontogenesis

Identifiers

PMID34641117
PMCPMC8512667
OpenAlexW3204166935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.