Evidence map›Paper›PMID 34640898›Full record

ReviewSensors (Basel, Switzerland)2021

Electrochemical Impedance Spectroscopy (EIS): Principles, Construction, and Biosensing Applications.

Hend S Magar, Rabeay Y A Hassan, Ashok Mulchandani

Open access · goldAbstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 234 papers.

0numbers the graph read from it
0cells of the map it votes in
234citing papers in PubMed
52.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

234 citing papers in PubMed, 1,149 citations in OpenAlex.

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  5. Boosting HER/OER Activity of Ni-FeOOH Through S and V Co-Doping.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026
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174 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Hend S MagarApplied Organic Chemistry Department, National Research Centre (NRC), Dokki, Giza 12622, Egypt.ORCID 0000-0003-3759-4060
Rabeay Y A HassanApplied Organic Chemistry Department, National Research Centre (NRC), Dokki, Giza 12622, Egypt.ORCID 0000-0002-1867-9643
Ashok MulchandaniDepartment of Chemical and Environmental Engineering, University of California Riverside, Riverside, CA 92521, USA.ORCID 0000-0002-2831-4154
National Research Centre · EGUniversity of California, Riverside · US

Funding

National Institute of Justice 2019-NE-BX-006
6 · The paper itself

Abstract

Electrochemical impedance spectroscopy (EIS) is a powerful technique used for the analysis of interfacial properties related to bio-recognition events occurring at the electrode surface, such as antibody-antigen recognition, substrate-enzyme interaction, or whole cell capturing. Thus, EIS could be exploited in several important biomedical diagnosis and environmental applications. However, the EIS is one of the most complex electrochemical methods, therefore, this review introduced the basic concepts and the theoretical background of the impedimetric technique along with the state of the art of the impedimetric biosensors and the impact of nanomaterials on the EIS performance. The use of nanomaterials such as nanoparticles, nanotubes, nanowires, and nanocomposites provided catalytic activity, enhanced sensing elements immobilization, promoted faster electron transfer, and increased reliability and accuracy of the reported EIS sensors. Thus, the EIS was used for the effective quantitative and qualitative detections of pathogens, DNA, cancer-associated biomarkers, etc. Through this review article, intensive literature review is provided to highlight the impact of nanomaterials on enhancing the analytical features of impedimetric biosensors.

Indexed as

Biosensing TechniquesNanocompositesDielectric SpectroscopyElectrochemical TechniquesReproducibility of Resultselectrochemical impedance spectroscopy (EIS)impedimetric biosensorsnanomaterials

Identifiers

PMID34640898
PMCPMC8512860
OpenAlexW3202325891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.