ReviewJournal of clinical medicine2021
Myocardial Work by Echocardiography: Principles and Applications in Clinical Practice.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.
- Non-Invasive Myocardial Work Indices (GWI, GCW, GWW, and GWE) as Predictors of Clinical Outcomes Across Cardiac Diseases: A Systematic Review and Meta-Analysis.Echocardiography (Mount Kisco, N.Y.) · 2026Pooled it
- Left Ventricular Mechanics and Myocardial Work in Competitive Sprinters.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Assessing myocardial work to predict left ventricular remodeling after ST-segment elevation myocardial infarction: associations with left atrial and left ventricular strain.Journal of cardiovascular imaging · 2026Article
- Dynamic Changes in Myocardial Function Early and Long-Term After Mitral Valve Surgery Detected by Speckle-Tracking Echocardiography.Journal of clinical medicine · 2026Article
- Incorporating Ventricular Geometry into the Myocardial Work Index: A Proof-of-Concept Study.Biomedicines · 2026Article
- Association of Glucose-Lowering Therapy with Myocardial Work Recovery and Reverse Remodeling After STEMI.Journal of clinical medicine · 2026Article
- Additional Role of Myocardial Work in Prognostic Stratification of Patients with Severe Aortic Regurgitation Undergoing Aortic Valve Surgery.Diagnostics (Basel, Switzerland) · 2026Article
- Echocardiographic Parameters and Athlete Performance: Associations and Training Profile Comparisons.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Physiological characterization of pressure-strain loops indices as non-invasive surrogates for ventriculo-arterial coupling: a proof-of-concept study.Scientific reports · 2026Article
- Prognostic value of myocardial work indices measured on echocardiography in patients with aortic stenosis undergoing transcatheter aortic valve replacement: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2026Article
- Prognostic Value of Non-Invasively Determined Right Ventricular-Arterial Coupling Surrogate Parameters in Patients with Dilated Cardiomyopathy.Journal of clinical medicine · 2026Article
- Integrative Assessment of Left Ventricular Myocardial Work: Prognostic Utility and Clinical Application Across Cardiovascular Pathologies.Journal of clinical medicine · 2026Review
- Development and validation of a diagnostic nomogram to predict significant stenosis of the left anterior descending branch of the coronary artery by stress echocardiography.Quantitative imaging in medicine and surgery · 2025Article
- Mid- to long-term mechanical performance of left bundle branch area pacing: a comprehensive echocardiographic comparison of capture modalities.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
- Effect of Transcatheter Aortic Valve Implantation on Non-Invasive Myocardial Work Parameters: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Sex-Specific Patterns and Predictors of Reverse Left Ventricular Remodeling and Outcomes in STEMI Patients with LVEF ≤ 50% After Successful Primary Angioplasty.Biomedicines · 2025Article
- Prognostic Significance of Left Ventricular Global Work Efficiency in Obese Patients with Acute ST-Segment Elevation Myocardial Infarction-A Pilot Study.Diagnostics (Basel, Switzerland) · 2025Article
- Myocardial Performance Improvement After Iron Replacement in Heart Failure Patients: The IRON-PATH II Echo-Substudy.Journal of clinical medicine · 2025Article
- Standard and advanced echocardiographic study of patients with Paget's disease of bone: Evidence of a pagetic heart disease?Journal of internal medicine · 2025Article
- Evaluating electrical stability in left bundle branch area pacing for bradycardia patients at follow-up.Heart rhythm O2 · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Left ventricular (LV) global longitudinal strain (GLS) has established itself in the last decade as a reliable, more objective method for the evaluation of LV systolic function, able to detect subtle abnormalities in LV contraction even in the presence of preserved ejection fraction (EF). However, recent studies have demonstrated that GLS, similar to LV EF, has important load dependency. Non-invasive myocardial work (MW) quantification has emerged in the last years as an alternative tool for myocardial function assessment. This new method, incorporating measurement of strain and LV pressure, has shown to overcome GLS and LV EF limitations and provide a loading-independent evaluation of myocardial performance. The presence of a commercially available echocardiographic software for the non-invasive MW calculation has allowed the application of this new method in different settings. This review sought to provide an overview on the current knowledge of non-invasive MW estimation, showing its potential applications and possible added value in clinical practice.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.