Evidence map›Paper›PMID 34640510›Full record

ReviewJournal of clinical medicine2021

Correlation between α1-Antitrypsin Deficiency and SARS-CoV-2 Infection: Epidemiological Data and Pathogenetic Hypotheses.

Andrea Vianello, Gabriella Guarnieri, Fausto Braccioni, Beatrice Molena, Sara Lococo, Alessia Achille, Federico Lionello, Leonardo Salviati, Marco Caminati, Gianenrico Senna

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Andrea VianelloDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35122 Padova, Italy.ORCID 0000-0002-8790-6029
Gabriella GuarnieriDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35122 Padova, Italy.ORCID 0000-0003-3664-2024
Fausto BraccioniDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35122 Padova, Italy.
Beatrice MolenaDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35122 Padova, Italy.
Sara LococoDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35122 Padova, Italy.
Alessia AchilleDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35122 Padova, Italy.
Federico LionelloDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35122 Padova, Italy.
Leonardo SalviatiDepartment of Pediatrics, University of Padova, 35122 Padova, Italy.
Marco CaminatiAsthma Center and Allergy Unit, University of Verona, 37129 Verona, Italy.ORCID 0000-0001-7383-1487
Gianenrico SennaAsthma Center and Allergy Unit, University of Verona, 37129 Verona, Italy.
University of Padua · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The most common hereditary disorder in adults, α1-antitrypsin deficiency (AATD), is characterized by reduced plasma levels or the abnormal functioning of α1-antitrypsin (AAT), a major human blood serine protease inhibitor, which is encoded by the SERine Protein INhibitor-A1 (

Indexed as

COVID-19geneticsSARS-CoV-2α1-antitrypsin deficiency

Identifiers

PMID34640510
PMCPMC8509830
OpenAlexW3203948719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.