Evidence map›Paper›PMID 34640472›Full record

ArticleJournal of clinical medicine2021

Assessment of Inter-Institutional Post-Operative Hypoparathyroidism Status Using a Common Data Model.

Joon-Hyop Lee, Suhyun Kim, Kwangsoo Kim, Young Jun Chai, Hyeong Won Yu, Su-Jin Kim, June Young Choi, Yoo Seung Chung, Kyu Eun Lee, Ka Hee Yi

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Joon-Hyop LeeGil Medical Center, Department of Surgery, Gachon University College of Medicine, Incheon 21565, Korea.ORCID 0000-0003-0470-7719
Suhyun KimDepartment of Applied Statistics, Chung-Ang University, Seoul 06974, Korea.
Kwangsoo KimTransdisciplinary Department of Medicine & Advanced Technology, Seoul National University Hospital, Seoul 03080, Korea.ORCID 0000-0002-4586-5062
Young Jun ChaiTransdisciplinary Department of Medicine & Advanced Technology, Seoul National University Hospital, Seoul 03080, Korea.ORCID 0000-0001-8830-3433
Hyeong Won YuDepartment of Surgery, Seoul National University Bundang Hospital, Seongnam 13620, Korea.ORCID 0000-0001-7338-5157
Su-Jin KimDepartment of Surgery, Seoul National University College of Medicine, Seoul National University Hospital, Seoul 03080, Korea.
June Young ChoiDepartment of Surgery, Seoul National University Bundang Hospital, Seongnam 13620, Korea.ORCID 0000-0001-9990-607X
Yoo Seung ChungGil Medical Center, Department of Surgery, Gachon University College of Medicine, Incheon 21565, Korea.
Kyu Eun LeeDepartment of Surgery, Seoul National University College of Medicine, Seoul National University Hospital, Seoul 03080, Korea.ORCID 0000-0002-2354-3599
Ka Hee YiDepartment of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul 07061, Korea.
Seoul National University Hospital · KRGachon University · KRSeoul National University · KRSeoul National University Bundang Hospital · KR

Funding

National Research Foundation of Korea No.2019R1C1C1008384Seoul National University College of Medicine Research Foundation Research Program 2019 800-20190517
6 · The paper itself

Abstract

Post-thyroidectomy hypoparathyroidism may result in various transient or permanent symptoms, ranging from tingling sensation to severe breathing difficulties. Its incidence varies among surgeons and institutions, making it difficult to determine its actual incidence and associated factors. This study attempted to estimate the incidence of post-operative hypoparathyroidism in patients at two tertiary institutions that share a common data model, the Observational Health Data Sciences and Informatics. This study used the Common Data Model to extract explicitly specified encoding and relationships among concepts using standardized vocabularies. The EDI-codes of various thyroid disorders and thyroid operations were extracted from two separate tertiary hospitals between January 2013 and December 2018. Patients were grouped into no evidence of/transient/permanent hypoparathyroidism groups to analyze the likelihood of hypoparathyroidism occurrence related to operation types and diagnosis. Of the 4848 eligible patients at the two institutions who underwent thyroidectomy, 1370 (28.26%) experienced transient hypoparathyroidism and 251 (5.18%) experienced persistent hypoparathyroidism. Univariate logistic regression analysis predicted that, relative to total bilateral thyroidectomy, radical tumor resection was associated with a 48% greater likelihood of transient hypoparathyroidism and a 102% greater likelihood of persistent hypoparathyroidism. Moreover, multivariate logistic analysis found that radical tumor resection was associated with a 50% greater likelihood of transient hypoparathyroidism and a 97% greater likelihood of persistent hypoparathyroidism than total bilateral thyroidectomy. These findings, by integrating and analyzing two databases, suggest that this analysis could be expanded to include other large databases that share the same Observational Health Data Sciences and Informatics protocol.

Indexed as

common data modelhypoparathyroidismincidencerisk factorsthyroidectomy

Identifiers

PMID34640472
PMCPMC8509408
OpenAlexW3204338555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.