Evidence map›Paper›PMID 34640442›Full record

ArticleJournal of clinical medicine2021

Real-Life Analysis with Erenumab: First Target Therapy in the Episodic and Chronic Migraine's Prophylaxis.

Zaira Maraia, Diletta Ricci, Marco Bruno Luigi Rocchi, Alessandro Moretti, Celestino Bufarini, Arturo Cavaliere, Manola Peverini

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Zaira MaraiaBiomolecular Sciences Department, University of Urbino, 61029 Urbino, Italy.
Diletta RicciBiomolecular Sciences Department, University of Urbino, 61029 Urbino, Italy.
Marco Bruno Luigi RocchiBiomolecular Sciences Department, University of Urbino, 61029 Urbino, Italy.ORCID 0000-0002-0056-5795
Alessandro MorettiNeurological Centre for Cognitive Disorders and Dementia, ASUR Marche AV1, 61034 Fossombrone, Italy.
Celestino BufariniUrbino Hospital Pharmacy, ASUR Marche AV1, 61029 Urbino, Italy.
Arturo CavaliereLocal Pharmaceutical Service, Viterbo Local Health Authority, 01100 Viterbo, Italy.
Manola PeveriniUrbino Hospital Pharmacy, ASUR Marche AV1, 61029 Urbino, Italy.
University of Urbino · ITAzienda Sanitaria Locale Viterbo · ITMarche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundto research retrospectively the efficacy of Erenumab's treatment, thus allowing to describe a summary more in line with the reality observed every day in clinical practice, relative to a sample of patients widely heterogeneous. The study aims to confirm the efficacy of Erenumab, in terms of reduction of migraine days per month, from baseline to month 12 of treatment. Additional objectives included a reduction in the number of days of symptomatic drug use and change from baseline in the Migraine Disability Assessment Score Questionnaire (MIDAS); Methods: the analysis included all patients treated for 12 months with Erenumab during the year 2019-2020. The population analyzed consists of twenty-six patients from the Neurology outpatient clinic in Fossombrone. Several quantitative and qualitative variables were recorded by reading the medical records of the patients. The MIDAS was administered to patients to assess the disability related to migraine; Results: at the end of treatment, a statistically significant reduction in the mean number of monthly migraine days, acute medication use per month, and MIDAS questionnaire score was observed; Conclusions: as a preventive treatment of episodic and chronic migraine, our analysis data confirm the efficacy of Erenumab for the prevention of the migraine. The success is achieved in 96% of cases.

Indexed as

CGRPErenumabMIDASmigrainereal-life analysis

Identifiers

PMID34640442
PMCPMC8509525
OpenAlexW3201981196

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.