ArticleJournal of clinical medicine2021
XEN Glaucoma Implant for the Management of Glaucoma in Naïve Patients versus Patients with Previous Glaucoma Surgery.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Minimally Invasive Bleb Surgery for Glaucoma: A Health Technology Assessment.Ontario health technology assessment series · 2024Pooled it
- The Outcomes of XEN Gel Stent Implantation: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2022Pooled it
- Factors influencing the long-term-success of the XEN gel stent.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Update on XEN Gel Stent: A Narrative Review on Indications, Surgical Technique, and Postoperative Management.Ophthalmology and therapy · 2026Review
- One-Year Outcomes of Repeat XEN Gel Stent Implantation for Prior XEN Failure: A Retrospective Study.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- XEN‑45 implantation for refractory secondary glaucoma.BMC ophthalmology · 2025Article
- Ab-Externo XEN Gel stent implantation effectively treated refractory glaucoma with prior failed shunt tube.BMC ophthalmology · 2024Article
- Double implantation of Xen 45 gel stent in primary open-angle glaucoma: a pilot study.International ophthalmology · 2024Article
- Swiss Multicenter Ab Interno XEN45 Gel Stent Study: 2-Year Real-World Data.Ophthalmology and therapy · 2024Article
- 36-Month Outcomes of Standalone Kahook Dual Blade Goniotomy Compared with Ab-Interno Closed Conjunctiva Xen Gel Stent Implantation.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Bleb Morphology on Anterior-Segment Optical Coherence Tomography after XEN Gel Stent Implantation.Journal of clinical medicine · 2023Article
- Recanalization of Xen45 gel stent implant occlusion using 10 - 0 nylon suture in refractory glaucoma: a case report.BMC ophthalmology · 2023Article
- Effectiveness and Safety of Xen Gel Stent in Glaucoma Surgery: A Systematic Review of the Literature.Journal of clinical medicine · 2023Review
- XEN® implantation: an effective strategy to stop glaucoma progression despite prior minimally invasive glaucoma surgery.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Defining the role of ab externo Xen gel stent in glaucomatous eyes with prior failed surgical intervention.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- XEN Gel Stent Implantation in Eyes With Previous Glaucoma Filtering Surgeries: A Case Series.Cureus · 2022Article
- Special Issue "Recommendations for Clinical Management of Glaucoma".Journal of clinical medicine · 2022Article
- Impact of Primary Needling on the XEN Implant Clinical Outcomes: A Real-Life Retrospective Study.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Ab Interno XEN Gel Stent Implantation in Eyes with Previous Tube Shunt Surgery.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This retrospective study analyzed the surgical and refractive outcomes of a XEN Gel Implant (Allergan, Abbvie Company, Irvine, CA, USA) in naïve patients versus those with previous glaucoma surgery. We evaluated the efficacy of XEN implantation in 86 glaucoma patients during a long-term follow-up period. Patients were divided into two groups: naïve patients (Group 1) and patients with previous glaucoma surgery (Group 2). Eyes that received a XEN Gel Stent placement from December 2014 to October 2019 were included. Intraocular pressure (IOP) change, corrected distance visual acuity (CDVA), change in glaucoma medications, frequency of slit lamp revision procedures, and frequency of secondary glaucoma surgeries were the primary outcomes. In Group 1, the mean IOP before surgery was decreased significantly from 25.00 ± 7.52 mmHg to 16.83 ± 5.12 mmHg by the end of the study. In Group 2, the mean IOP decreased significantly from 25.35 ± 7.81 mmHg to 17.54 ± 5.34 mmHg. The mean IOP decrease from baseline was 29% in Group 1 and 27% in Group 2 (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.