ReviewJournal of clinical medicine2021
Current Management Options in Irvine-Gass Syndrome: A Systemized Review.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Non-steroidal anti-inflammatory agents for treating cystoid macular edema following cataract surgery.The Cochrane database of systematic reviews · 2022Pooled it
- Inflammation and patient satisfaction in micropulse versus continuous wave transscleral cyclophotocoagulation.The British journal of ophthalmology · 2025Trial
- Article
- Layer-Specific Retinal Perfusion as a Personalized Biomarker: Evaluating the Subclinical Microanatomical Effects of Intracameral Cefuroxime After Routine Cataract Surgery.Journal of personalized medicine · 2026Article
- Comparison of topical nepafenac 0.1% and 0.3% for the treatment of pseudophakic cystoid macular edema following cataract surgery.BMC ophthalmology · 2026Article
- When Postoperative Inflammation Isn't Benign: Thyroid Eye Disease Following Cataract Surgery.Cureus · 2025Article
- Irvine-Gass Syndrome Personalized Treatment Outcomes: A Retrospective Single-Center Cohort Study.Journal of personalized medicine · 2025Article
- Systemic inflammatory response index as a predictive biomarker for Irvine-Gass syndrome.International ophthalmology · 2025Article
- Review
- Radial Peripapillary Capillary Vessel Density as a New Biomarker in Pseudophakic Cystoid Macular Edema.Journal of clinical medicine · 2025Article
- Treatment of pseudophakic aqueous misdirection syndrome.Scientific reports · 2025Article
- Phacoemulsification surgery in patients with diabetic macular edema: should intravitreal anti-VEGF therapy be performed before or simultaneously with surgery?International journal of ophthalmology · 2025Article
- Incidence and Remission of Post-Surgical Cystoid Macular Edema Following Cataract Surgery in Eyes With Intraocular Inflammation.American journal of ophthalmology · 2024Article
- Assessment of the Retinal Ganglion Cell Layer after Uncomplicated Cataract Surgery.Journal of clinical medicine · 2024Article
- Choroidal and Retinal Thicknesses in Healthy Eyes Measured with Ultra-Wide-Field Optical Coherence Tomography.Diagnostics (Basel, Switzerland) · 2024Article
- Navigated yellow subthreshold micropulse laser for refractory cystoid macular edema following rhegmatogenous retinal detachment surgery.American journal of ophthalmology case reports · 2024Article
- Real-world treatment patterns and economic burden of post-cataract macular edema.BMC ophthalmology · 2023Article
- Correlation between Severity of Idiopathic Epiretinal Membrane and Irvine-Gass Syndrome.Journal of personalized medicine · 2023Article
- [Pseudophakic cystoid macular edema : Statement of the German Society of Ophthalmology, the German Retina Society and the German Professional Association of Ophthalmologists. Status 22 October 2022].Die Ophthalmologie · 2023Review
- Case Report: Intravitreal Aflibercept for Refractory Irvine-Gass Syndrome.Case reports in ophthalmologyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Irvine-Gass syndrome (IGS) remains one of the most common complications following uneventful cataract surgery. In most cases, macular edema (ME) in IGS is benign, self-limiting, and resolves spontaneously without visual impairment; however, persistent edema and refractory cases may occur and potentially deteriorate visual function. Despite the relatively high prevalence of IGS, no solid management guidelines exist. We searched the PUBMED database for randomized clinical trials (RCT) or case series of at least 10 cases published since 2000 evaluating different treatment strategies in patients with cystoid macular edema (CME). The search revealed 28 papers that fulfilled the inclusion criteria with only seven RCTs. The scarceness of material makes it impossible to formulate strong recommendations for the treatment of IGS. Clinical practice and theoretical background support topical non-steroidal anti-inflammatory drugs (NSAIDs) as the first-line therapy. Invasive procedures, such as periocular steroids, intravitreal corticosteroids, and anti-vascular endothelial growth factor (anti-VEGF), are usually applied in prolonged or refractory cases. Results of novel applications of subthreshold micropulse laser (SML) are also promising and should be studied carefully in terms of the safety profile and cost effectiveness. Early initiation of invasive treatment for providing better functional results must be examined in further research.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.