Evidence map›Paper›PMID 34640381›Full record

ArticleJournal of clinical medicine2021

Neutrophil-to-Lymphocyte Ratios and Infections after Traumatic Brain Injury: Associations with Hospital Resource Utilization and Long-Term Outcome.

Marina Levochkina, Leah McQuillan, Nabil Awan, David Barton, John Maczuzak, Claudia Bianchine, Shannon Trombley, Emma Kotes, Joshua Wiener, Audrey Wagner and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Marina LevochkinaDepartment of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Leah McQuillanDepartment of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Nabil AwanDepartment of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA.
David BartonDepartment of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
John MaczuzakDepartment of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Claudia BianchineDepartment of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Shannon TrombleyDepartment of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Emma KotesDepartment of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Joshua WienerDepartment of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Audrey WagnerDepartment of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Jason CalcagnoDepartment of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Andrew MazaDepartment of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Ryan NierstedtDepartment of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Stephanie FerimerDivision of Pediatric Rehabilitation Medicine, Department of Orthopaedics, West Virginia University, Morgantown, WV 26506, USA.
Amy WagnerDepartment of Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15213, USA.
University of Pittsburgh · USWest Virginia University · US

Funding

Emergency Medicine Research TrainingT32HL134615 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Clifton W. Callaway, DONALD M YEALY · 2017 to 2026
$2.4M
Dopamine Genetic Variants Modulating Recovery After TBIR01HD048162 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WAGNER, AMY K · 2004 to 2008
$1.8M
CDC HHS R49-CCR-323155National Institute on Disability, Independent Living, and Rehabilitation Research 90DP004NHLBI NIH HHS T32 HL134615NIH HHS R01 HD048162NIH HHS T32HL134615U.S. Department of Defense DoDW81XWH19-2-0012U.S. Department of Defense W81XWH-071-0701
6 · The paper itself

Abstract

Traumatic brain injury (TBI) induces immune dysfunction that can be captured clinically by an increase in the neutrophil-to-lymphocyte ratio (NLR). However, few studies have characterized the temporal dynamics of NLR post-TBI and its relationship with hospital-acquired infections (HAI), resource utilization, or outcome. We assessed NLR and HAI over the first 21 days post-injury in adults with moderate-to-severe TBI (

Indexed as

Glasgow outcome scalehospital acquired infectionhospital resource utilizationinflammationmechanical ventilationneutrophil-to-lymphocyte ratiotraumatic brain injury

Identifiers

PMID34640381
PMCPMC8509449
OpenAlexW3203314854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.