ReviewJournal of clinical medicine2021
Potential Nociceptive Role of the Thoracolumbar Fascia: A Scope Review Involving In Vivo and Ex Vivo Studies.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 30 citations in OpenAlex.
- Quantitative ultrasound evaluation of the thoracolumbar fascia after manual and acupuncture therapies: an exploratory mechanistic randomized controlled trial with a sequential within-subject phase.European radiology experimental · 2026Trial
- Article
- Ultrasonographic Evaluation of Superior Cluneal Nerve Entrapment: Methodological Considerations. Comment on Iudicelli et al. The Role of Musculoskeletal Ultrasound in Detecting Superior Cluneal Nerve Entrapment: Biomechanical Insights in Chronic Low Back Pain-A Pilot Study.Diagnostics (Basel, Switzerland) · 2026Article
- Cocktail injection with ropivacaine and compound betamethasone for preoperative thoracolumbar fascia injury effectively reduces postoperative pain and the risk of short-term postoperative residual pain during vertebral augmentation in the treatment of osteoporotic vertebral fractures: a retrospective controlled study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Fascia as a Functional System in Health and Disease: From Fundamental Biology to Assessment and Targeted Interventions.International journal of molecular sciences · 2026Review
- A systematic scoping review and conceptual analysis of new-onset fibromyalgia manifestations after non-hospitalized COVID-19: empirics, definitions, methodologies, pathophysiology, mapping of literature, and knowledge gaps.Journal of translational medicine · 2026Article
- Combined vertebroplasty and pregabalin versus vertebroplasty alone for osteoporotic thoracolumbar fractures with referred pain: a retrospective cohort study.BMC musculoskeletal disorders · 2026Article
- From mechanotransduction to manual therapy: advances in piezo/TRP channels and lumbar degeneration.Frontiers in physiology · 2026Review
- Risk factors of thoracolumbar fascia injury for patients with Parkinson's disease and construction of a nomogram model.BMC neurology · 2025Article
- An Emerging Perspective on the Role of Fascia in Complex Regional Pain Syndrome: A Narrative Review.International journal of molecular sciences · 2025Review
- Thoracolumbar fascia ultrasound shear strain differs between low back pain and asymptomatic individuals: expanding the evidence.Insights into imaging · 2025Article
- Bio-tensegrity and extracellular matrix disruption in the pathogenesis of persistent post-operative pain: a hypothesis.Frontiers in physiology · 2025Article
- Comparative study of thoracolumbar fascia changes in weightlifters with and without low back pain.PloS one · 2025Article
- Exploring fascia in myofascial pain syndrome: an integrative model of mechanisms.Frontiers in pain research (Lausanne, Switzerland) · 2025Review
- Pain quality patterns in delayed onset muscle soreness of the lower back suggest sensitization of fascia rather than muscle afferents: a secondary analysis study.Pflugers Archiv : European journal of physiology · 2024Article
- Shear wave elastography based analysis of changes in fascial and muscle stiffness in patients with chronic non-specific low back pain.Frontiers in bioengineering and biotechnology · 2024Article
- Fascia Tissue Manipulations in Chronic Low Back Pain: A Pragmatic Comparative Randomized Clinical Trial of the 4xT MethodLife (Basel, Switzerland) · 2023Article
- Comparison of thoracolumbar versus non-thoracolumbar osteoporotic vertebral compression fractures in risk factors, vertebral compression degree and pre-hospital back pain.Journal of orthopaedic surgery and research · 2023Article
- Biomechanical Phenotyping of Chronic Low Back Pain: Protocol for BACPAC.Pain medicine (Malden, Mass.) · 2023Article
- Unlocking Pain Relief for Chronic Low Back Pain: The Potential of the 4xT Method® - A Dual Case Study Analysis.The American journal of case reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nociceptive innervation of the thoracolumbar fascia (TLF) has been investigated over the past few decades; however, these studies have not been compiled or collectively appraised. The purpose of this scoping review was to assess current knowledge regarding nociceptive innervation of the TLF to better inform future mechanistic and clinical TLF research targeting lower back pain (LBP) treatment. PubMed, ScienceDirect, Cochrane, and Embase databases were searched in January 2021 using relevant descriptors encompassing fascia and pain. Eligible studies satisfied the following: (a) published in English; (b) preclinical and clinical (in vivo and ex vivo) studies; (c) original data; (d) included quantification of at least one TLF nociceptive component. Two-phase screening procedures were conducted by a pair of independent reviewers, after which data were extracted and summarized from eligible studies. The search resulted in 257 articles of which 10 met the inclusion criteria. Studies showed histological evidence of nociceptive nerve fibers terminating in lower back fascia, suggesting a TLF contribution to LBP. Noxious chemical injection or electrical stimulation into fascia resulted in longer pain duration and higher pain intensities than injections into subcutaneous tissue or muscle. Pre-clinical and clinical research provides histological and functional evidence of nociceptive innervation of TLF. Additional knowledge of fascial neurological components could impact LBP treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.