Evidence map›Paper›PMID 34639798›Full record

ArticleInternational journal of environmental research and public health2021

Utility of Self-Reported Heat Stress Symptoms and NGAL Biomarker to Screen for Chronic Kidney Disease of Unknown Origin (CKDu) in Sri Lanka.

Pavithra N Kulasooriya, Kithsiri B Jayasekara, Thilini Nisansala, Sajani Kannangara, Ranawaka Karunarathna, Chaminda Karunarathne, Mahinda Wikramarathne, Steven M Albert

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Recent ambient temperature and fine particulate matter (PMThe Science of the total environment · 2024
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Pavithra N KulasooriyaUniversity Hospital, Sir John Kotelawala Defence University, Colombo 10290, Sri Lanka.
Kithsiri B JayasekaraFaculty of Allied Health Sciences, Sir John Kotelawala Defence University, Colombo 10290, Sri Lanka.
Thilini NisansalaUniversity Hospital, Sir John Kotelawala Defence University, Colombo 10290, Sri Lanka.
Sajani KannangaraFaculty of Allied Health Sciences, Sir John Kotelawala Defence University, Colombo 10290, Sri Lanka.
Ranawaka KarunarathnaProvincial Directors' Office, Anuradhapura 5000, Sri Lanka.
Chaminda KarunarathneFaculty of Allied Health Sciences, Sir John Kotelawala Defence University, Colombo 10290, Sri Lanka.
Mahinda WikramarathneFaculty of Allied Health Sciences, University of Peradeniya, Kandy 20400, Sri Lanka.
Steven M AlbertDepartment of Behavioral and Community Health Sciences, University of Pittsburgh, Pittsburgh, PA 15621, USA.ORCID 0000-0001-6786-9956
General Sir John Kotelawala Defence University · LKUniversity of Peradeniya · LKRajarata University of Sri Lanka · LKUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe examined heat stress symptoms and urine markers of chronic kidney disease (CKDu) in Sri Lanka to assess differences between endemic vs. non-endemic regions and by occupation. SAMPLE AND

methodsWe assessed a total of 475 villagers. In the endemic region, 293 were agricultural workers and 67 were not working primarily in agriculture. In the non-endemic region, 76 were agricultural workers. Of the residents, 218 were assessed for neutrophil gelatinase-associated lipocalin (NGAL), an early predictor of acute kidney injury, along with urine markers of chronic kidney disease.

resultsThe mean (sd) age of the sample was 45.2 (12.6), with males comprising 52.7%; 7.2% reported kidney disease (

conclusionsBoth heat stress symptoms and NGAL values were higher among agricultural workers in endemic CKDu regions. Correlations between NGAL and microalbumin suggested a link between acute kidney injury and chronic kidney disease in the more-exposed sample.

Indexed as

Renal Insufficiency, ChronicBiomarkersHeat-Shock ResponseHumansLipocalin-2MaleSelf ReportSri LankaBiomarkersLipocalin-2agriculturechronic kidney diseaseheat stressNGALSri Lanka

Identifiers

PMID34639798
PMCPMC8507708
OpenAlexW3202095993

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.