Evidence map›Paper›PMID 34639764›Full record

ReviewInternational journal of environmental research and public health2021

Environmental/Occupational Exposure to Radon and Non-Pulmonary Neoplasm Risk: A Review of Epidemiologic Evidence.

Paola Mozzoni, Silvana Pinelli, Massimo Corradi, Silvia Ranzieri, Delia Cavallo, Diana Poli

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Experimental Setups for In Vitro Studies on Radon Exposure in Mammalian Cells-A Critical Overview.International journal of environmental research and public health · 2023
    Review
  12. Article
  13. Article
  14. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Paola MozzoniDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0002-6883-8040
Silvana PinelliDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Massimo CorradiDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Silvia RanzieriDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0002-9607-8624
Delia CavalloINAIL Research, Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Via Fontana Candida 1, 00078 Monte Porzio Catone, Italy.ORCID 0000-0002-2331-1464
Diana PoliINAIL Research, Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Via Fontana Candida 1, 00078 Monte Porzio Catone, Italy.
University of Parma · ITIstituto Nazionale per l'Assicurazione Contro gli Infortuni sul Lavoro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although Radon (Rn) is a known agent for lung cancer, the link between Rn exposure and other non-pulmonary neoplasms remains unclear. The aim of this review is to investigate the role of Rn in the development of tumors other than lung cancer in both occupational and environmental exposure. Particularly, our attention has been focused on leukemia and tumors related to brain and central nervous system (CNS), skin, stomach, kidney, and breast. The epidemiologic literature has been systematically reviewed focusing on workers, general population, and pediatric population. A weak increase in leukemia risk due to Rn exposure was found, but bias and confounding factors cannot be ruled out. The results of studies conducted on stomach cancer are mixed, although with some prevalence for a positive association with Rn exposure. In the case of brain and CNS cancer and skin cancer, results are inconclusive, while no association was found for breast and kidney cancers. Overall, the available evidence does not support a conclusion that a causal association has been established between Rn exposure and the risk of other non-pulmonary neoplasms mainly due to the limited number and heterogeneity of existing studies. To confirm this result, a statistical analysis should be necessary, even if it is now not applicable for the few studies available.

Indexed as

Lung NeoplasmsOccupational ExposureRadonChildEnvironmental ExposureHumansRadoncancer riskenvironmental exposureepidemiological studiesoccupational exposureradon

Identifiers

PMID34639764
PMCPMC8508162
OpenAlexW3206931001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.