Evidence map›Paper›PMID 34639701›Full record

ArticleInternational journal of environmental research and public health2021

Influence of Female Sex Hormones on Ultra-Running Performance and Post-Race Recovery: Role of Testosterone.

Eladio Collado-Boira, Pablo Baliño, Ana Boldo-Roda, Ignacio Martínez-Navarro, Bárbara Hernando, Paula Recacha-Ponce, Carlos Hernando, María Muriach

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Female trail running: a systematic scoping review.Frontiers in sports and active living · 2025
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Elements Affecting Quality of Life in Individuals With Gastroesophagel Reflux Disease.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Eladio Collado-BoiraFaculty of Health Sciences, Jaume I University, 12071 Castellon, Spain.ORCID 0000-0001-8062-4152
Pablo BaliñoFaculty of Health Sciences, Jaume I University, 12071 Castellon, Spain.
Ana Boldo-RodaObstetrics and Gynecology, University Hospital of La Plana, 12540 Vila-Real, Spain.
Ignacio Martínez-NavarroDepartment of Physical Education and Sport, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0002-2942-1293
Bárbara HernandoFaculty of Health Sciences, Jaume I University, 12071 Castellon, Spain.
Paula Recacha-PonceFaculty of Health Sciences, Jaume I University, 12071 Castellon, Spain.ORCID 0000-0003-2092-8212
Carlos HernandoSport Service, Jaume I University, 12071 Castellon, Spain.ORCID 0000-0001-7182-4785
María MuriachFaculty of Health Sciences, Jaume I University, 12071 Castellon, Spain.
Universitat Jaume I · ESUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, increasing numbers of women have participated in extremely long races. In adult males, there is a clear association between physiological levels of endogenous sex hormones and physical performance. However, the influence of plasmatic sex hormones and the effects of different types of hormonal contraception (HC) on the modulation of physical performance in adult females remain to be fully clarified. Eighteen female ultra-endurance athletes were recruited to participate in the study. Different variables were studied, including hematological parameters, body mass index, and body composition. Strength measurements were obtained using the squat-jump and hand-grip test. A repeated-measures analysis demonstrated significant differences in hematological values of CK and LDH pre-race as compared to immediately post-race and after 24/48 h. Furthermore, statistical differences were found in squat-jump and hand-grip test results after the ultramarathon. Testosterone, estradiol, and the testosterone/estrogen ratio were significantly correlated with muscle fatigue and were found to be indirect markers of muscle damage. A multivariate analysis demonstrated the protective role of testosterone against muscle damage and severe fatigue. Fluctuations in endogenous testosterone levels were correlated with greater fatigability and muscle damage after the competition. Adjusting the menstrual cycle with HC would not provide any further benefit to the athlete's competitive capacity.

Indexed as

RunningTestosteroneAdultAthletesBiomarkersFemaleHumansMalePhysical EnduranceBiomarkersTestosteronefemale athleteshormonal contraceptionhormonesmuscle damagemuscle fatiguephysical performanceultra-endurance

Identifiers

PMID34639701
PMCPMC8508191
OpenAlexW3202360869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.