Evidence map›Paper›PMID 34639683›Full record

ReviewInternational journal of environmental research and public health2021

Web Axillary Pain Syndrome-Literature Evidence and Novel Rehabilitative Suggestions: A Narrative Review.

Francesco Agostini, Carmine Attanasi, Andrea Bernetti, Massimiliano Mangone, Marco Paoloni, Edoardo Del Monte, Massimo Mammucari, Enrica Maggiori, Domenico Russo, Raffaele Di Marzo and 2 more

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06269523 (Effects of Rehabilitation and Kinesio Taping to Prevent Axillary Web Syndrome After Breast Cancer Surgery), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06269523 nacompletednot on this map

Effects of Rehabilitation and Kinesio Taping to Prevent Axillary Web Syndrome After Breast Cancer Surgery

TypeinterventionalSponsorUniversity of PalermoRan2021 to 2024Enrolled18ConditionsAxillary Web SyndromeArmsKinesio taping, Lymphatic drainage, Lymphatic drainage
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Effectiveness of physical therapy in axillary web syndrome after breast cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  2. Trial
  3. Article
  4. Protocol to improve quality of life, functionality, and exercise capacity in patients with axillary web syndrome after breast cancer: a randomized clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Francesco AgostiniDepartment of Anatomical and Histological Sciences, Legal Medicine and Orthopedics, Sapienza University, 00185 Rome, Italy.ORCID 0000-0003-3162-3473
Carmine AttanasiPhysical Medicine and Rehabilitation Unit, Santa Caterina Novella Hospital, 73013 Lecce, Italy.ORCID 0000-0003-3556-8424
Andrea BernettiDepartment of Anatomical and Histological Sciences, Legal Medicine and Orthopedics, Sapienza University, 00185 Rome, Italy.
Massimiliano MangoneDepartment of Anatomical and Histological Sciences, Legal Medicine and Orthopedics, Sapienza University, 00185 Rome, Italy.
Marco PaoloniDepartment of Anatomical and Histological Sciences, Legal Medicine and Orthopedics, Sapienza University, 00185 Rome, Italy.ORCID 0000-0002-0947-9711
Edoardo Del MonteSan Camillo Forlanini School of Physiotherapy, 00152 Rome, Italy.
Massimo MammucariPrimary Care Unit ASL RM 1, 00193 Rome, Italy.ORCID 0000-0002-9515-3549
Enrica MaggioriPrimary Care Unit ASL RM 1, 00193 Rome, Italy.
Domenico RussoSan Marco Hospice and Palliative Care, 04100 Latina, Italy.
Raffaele Di MarzoItalian Society of Mesotherapy, 00185 Rome, Italy.
Alberto MiglioreUnit of Rheumatology, San Pietro Fatebenefratelli Hospital, 00186 Rome, Italy.
Teresa PaolucciDepartment of Oral Medical Science and Biotechnology, G. D'Annunzio University of Chieti-Pescara, 66100 Chieti, Italy.
Sapienza University of Rome · ITAzienda Sanitaria Locale Roma 3 · ITFatebenefratelli Hospital · ITItalian Society of Physiotherapy · ITUniversity of Chieti-Pescara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Axillary web syndrome (AWS) is defined as a visible and palpable network of cords in the skin of the axillary cavity that are tensed by shoulder abduction following surgery for breast cancer, causing significant functional limits of the ipsilateral upper limb (UL) and pain. The purpose of this narrative review is to discuss rehabilitation approaches for greater efficacy with respect to pain and novel suggestions. AWS is a frequent complication of axillary lymphadenectomy that necessitates a thorough follow-up in the medium to long term. Physiotherapy is effective in the treatment of functional limb deficits, the management of pain, and the treatment of upper limb disability. The best management approach involves the use of soft tissue techniques to slow the natural course of the syndrome, in association with therapeutic exercises for functional recovery and muscle strengthening. AWS is linked secondary lymphedema, requiring integration with manual lymphatic drainage. The physiotherapy management of AWS is currently fragmented, and insufficient information is available on the nature of the disease. Thus, randomized and controlled studies that compare rehabilitation approaches in AWS are desirable, including the possibility of using mesotherapy in the treatment of axillary and upper limb pain.

Indexed as

Breast NeoplasmsLymphedemaAxillaFemaleHumansLymph Node ExcisionPainPostoperative Complicationsaxillary web syndromebreast cancerlymphadenectomymesotherapyphysiotherapyrehabilitation

Identifiers

PMID34639683
PMCPMC8507961
OpenAlexW3204071948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.