ArticleInternational journal of environmental research and public health2021
Association of Pesticides and Kidney Function among Adults in the US Population 2001-2010.
Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Heterogeneity in diagnostic criteria for chronic kidney disease of undetermined etiology (CKDu): a systematic review of the literature.BMC nephrology · 2025Pooled it
- Low-dose exposure to organophosphate pesticides and chronic kidney disease: insights from urinary dialkyl phosphate biomarkers.Clinical and experimental nephrology · 2026Article
- Evidence-Based Assessment of Pesticide-Related Nephrotoxicity: Clinical Outcomes, Experimental Data, and Molecular Signatures.International journal of molecular sciences · 2026Review
- Apoptosis and Cell Cycle Dysregulation in AmpligoJournal of xenobiotics · 2026Article
- Multichemical Exposure Assessment Using Silicone Wristbands in Central American Adolescents.Exposure and health · 2026Article
- Specific Hepatorenal Toxicity and Cross-Species Susceptibility of Eight Representative Pesticides.Toxics · 2025Article
- Air Pollution, Kidney Injury, and Green Nephrology-Thinking About Its Association and Causation.Journal of clinical medicine · 2025Review
- Global, regional, and national trends in chronic kidney disease burden (1990-2021): a systematic analysis of the global burden of disease in 2021.Tropical medicine and health · 2025Article
- Global, regional, and national burden of chronic kidney disease and its underlying etiologies from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021.BMC public health · 2025Article
- Review
- Chronic kidney disease and the global public health agenda: an international consensus.Nature reviews. Nephrology · 2024Review
- Occupational risks associated with chronic kidney disease of non-traditional origin (CKDnt) in Brazil: it is time to dig deeper into a neglected problem.Jornal brasileiro de nefrologia · 2024Article
- Article
- The Hematological and Biochemical Effects from Pesticide Exposure on Thai Vegetable Farmers.Toxics · 2023Article
- Article
- Solving the riddle of Aguascalientes nephropathy: nephron number, environmental toxins and family clustering.Clinical kidney journal · 2022Article
- Aguascalientes: one of the hottest chronic kidney disease (CKD) hotspots in Mexico and a CKD of unknown aetiology mystery to be solved.Clinical kidney journal · 2021Article
- Pesticide Levels and Other Etiopathogenetic Factors in Patients with Chronic Kidney Disease of Unknown Cause in Central India - A Case-Control Study.Indian journal of nephrologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic kidney disease of unknown cause is prevalent in a range of communities; however, its etiology remains unclear. We examined the association between pesticide exposures and the risk of kidney function loss using four waves of the National Health and Nutrition Examination Survey (NHANES) to identify a pathological pathway. We pooled data from four cross-sectional waves of NHANES, with 41,847 participants in total. Exposure to malathion increased the risk of low kidney function (aOR = 1.26, 95% CI = 1.01-1.56) in the adjusted model. Increased risk of low kidney function was not found among those exposed to 2,4-D (aOR = 0.88, 95% CI = 0.72-1.09), 3,5,6-trichloropyridinol (aOR = 0.96, 95% CI = 0.83-1.12), and 3-PBA (aOR = 1.03, 95% CI = 0.94-1.13). Our findings provide evidence of altered kidney function in people exposed to malathion, highlighting the potential of organophosphate pesticides' role in renal injury.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.