Evidence map›Paper›PMID 34639458›Full record

ArticleInternational journal of environmental research and public health2021

Health-Related Quality of Life (HRQoL) Outcomes Following Injury in Childhood and Adolescence Using EuroQol (EQ-5D) Responses with Pooled Longitudinal Data.

Joanna F Dipnall, Frederick P Rivara, Ronan A Lyons, Shanthi Ameratunga, Mariana Brussoni, Fiona E Lecky, Clare Bradley, Ben Beck, Jane Lyons, Amy Schneeberg and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Function and Quality of Life 5 Years Following Pediatric Major Trauma: A Population-Based Cohort Study.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026
    Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Assessing Pediatric Traumatic Brain Injury and Health-Related Quality of Life in Three Eastern European Countries.Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Joanna F DipnallSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.ORCID 0000-0001-7543-0687
Frederick P RivaraDepartments of Pediatrics and Epidemiology, Harborview Injury Prevention and Research Center, University of Washington, Seattle, WA 98195, USA.
Ronan A LyonsSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.
Shanthi AmeratungaSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.ORCID 0000-0001-8042-2251
Mariana BrussoniDepartment of Pediatrics, School of Population and Public Health, University of British Columbia, Vancouver, BC V6H 3V4, Canada.ORCID 0000-0002-1495-816X
Fiona E LeckyCentre for Urgent and Emergency Care Research, School of Health and Related Research, University of Sheffield, Sheffield S10 2TN, UK.ORCID 0000-0001-6806-0921
Clare BradleySouth Australian Health and Medical Research Institute, Adelaide 5001, Australia.
Ben BeckSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.ORCID 0000-0003-3262-5956
Jane LyonsHealth Data Research UK, Swansea University, Swansea SA2 8PP, UK.
Amy SchneebergBritish Columbia Injury Research and Prevention Unit, British Columbia Children's Hospital Research Institute, Vancouver, BC V6H 3V4, Canada.
James E HarrisonCollege of Medicine and Public Health, Flinders University, Bedford Park 5042, Australia.
Belinda J GabbeSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.ORCID 0000-0001-7096-7688

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInjury is a leading contributor to the global disease burden in children, affecting their health-related quality of life (HRQoL)-yet valid estimates of burden are absent.

methodsThis study pooled longitudinal data from five cohort studies of pediatric injury survivors (5-17 years) at baseline, 1-, 4-, 6-, 12-, and 24- months (

resultsMean EQ-5D post-injury did not return to baseline level (0.95) by 24 months (0.88) and was lower for females over time (-0.04, 95%CI -0.05, -0.02). A decreased adjusted risk ratio over time (ARR) was observed for intentional injuries (pain: 0.85, 95%CI 0.73,0.98; anxiety: 0.62, 95%CI 0.49,0.78); spinal cord injuries (mobility: 0.61, 95%CI 0.45,0.83), self-care: 0.76, 95%CI 0.63,0.91, activity: 0.64, 95%CI 0.47,0.88); moderate/severe traumatic brain injury (activity: 0.83, 95%CI 0.71,0.96). ARRs were also low for certain fractures, with various health states affected.

conclusionsHRQoL outcomes over time for children and adolescents post-injury differed across key demographic and injury related attributes. HRQoL did not reach levels consistent with full health by 24 months with recovery plateauing from 6 to 24 months. Tailored interventions are required to respond to the varying post-injury recovery trajectories in this population.

Indexed as

Quality of LifeSurvivorsAdolescentAnxietyChildFemaleHumansPain MeasurementSelf CareSurveys and QuestionnairesadolescentschildrendisabilityEQ-5Dhealth outcomeshealth-related quality of lifeinjurypediatrictrauma

Identifiers

PMID34639458
PMCPMC8507627

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.