ArticleInternational journal of molecular sciences2021
Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- TmKayak functions as an effector of Jun N-terminal kinase pathway to modulate immune responses in Tenebrio molitor.Scientific reports · 2026Article
- A possible role of Painless channel in the regulation of immune system activity in Tenebrio molitor L.Scientific reports · 2026Article
- Tachykinin-related peptide signalling is important for the immune response of the mealworm beetleFrontiers in immunology · 2026Article
- Innate Immune Response ofInternational journal of molecular sciences · 2023Article
- Article
- Article
- Analysis of the Toll and Spaetzle Genes Involved in Toll Pathway-Dependent Antimicrobial Gene Induction in the Red Flour Beetle,International journal of molecular sciences · 2023Article
- Recent trends in insect gut immunity.Frontiers in immunology · 2023Review
- Immunological Roles ofInternational journal of molecular sciences · 2022Article
- Host-Pathogen Interaction 3.0.International journal of molecular sciences · 2022Article
- Emerging Evidence onMicroorganisms · 2022Review
- Antimicrobial peptides: Defending the mucosal epithelial barrier.Frontiers in oral health · 2022Review
- Current Status of Immune Deficiency Pathway inFrontiers in immunology · 2022Review
- Critical Roles of Spätzle5 in Antimicrobial Peptide Production AgainstFrontiers in immunology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
The cystine knot protein Spätzle is a Toll receptor ligand that modulates the intracellular signaling cascade involved in the nuclear factor kappa B (NF-κB)-mediated regulation of antimicrobial peptide (AMP)-encoding genes. Spätzle-mediated activation of the Toll pathway is critical for the innate immune responses of insects against Gram-positive bacteria and fungi. In this study, the open reading frame (ORF) sequence of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.