Evidence map›Paper›PMID 34639195›Full record

ArticleInternational journal of molecular sciences2021

Characterization of the Chimeric PriB-SSBc Protein.

En-Shyh Lin, Yen-Hua Huang, Cheng-Yang Huang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Crystal Structure of an SSB Protein fromInternational journal of molecular sciences · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

En-Shyh LinDepartment of Beauty Science, National Taichung University of Science and Technology, No. 193, Sec.1, San-Min Rd., Taichung City 403, Taiwan.ORCID 0000-0002-7010-4062
Yen-Hua HuangSchool of Biomedical Sciences, Chung Shan Medical University, No. 110, Sec.1, Chien-Kuo N. Rd., Taichung City 402, Taiwan.ORCID 0000-0001-6347-3030
Cheng-Yang HuangSchool of Biomedical Sciences, Chung Shan Medical University, No. 110, Sec.1, Chien-Kuo N. Rd., Taichung City 402, Taiwan.
Chung Shan Medical University · TWChung Shan Medical University Hospital · TWNational Taichung University of Science and Technology · TW

Funding

Chung Shan Medical University CSMU 109-F0190003Ministry of Science and Technology, Taiwan MOST 109-2622-E-025-006
6 · The paper itself

Abstract

PriB is a primosomal protein required for the replication fork restart in bacteria. Although PriB shares structural similarity with SSB, they bind ssDNA differently. SSB consists of an N-terminal ssDNA-binding/oligomerization domain (SSBn) and a flexible C-terminal protein-protein interaction domain (SSBc). Apparently, the largest difference in structure between PriB and SSB is the lack of SSBc in PriB. In this study, we produced the chimeric PriB-SSBc protein in which

Indexed as

Amino Acid SequenceBacterial ProteinsCrystallography, X-RayDNA-Binding ProteinsDNA ReplicationKlebsiella pneumoniaeModels, MolecularProtein ConformationProtein Interaction Domains and MotifsRecombinant Fusion ProteinsSequence HomologyBacterial ProteinsDNA-Binding ProteinsRecombinant Fusion ProteinsDNA mimicDnaTGGRQ motifOB foldPriAPriBPriB-SSBcprimosomereplication forkSSB

Identifiers

PMID34639195
PMCPMC8509808
OpenAlexW3203439720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.