Evidence map›Paper›PMID 34639111›Full record

ArticleInternational journal of molecular sciences2021

Comparison of Two Experimental Mouse Dry Eye Models through Inflammatory Gene Set Enrichment Analysis Based on a Multiplexed Transcriptomic Approach.

Karima Kessal, Philippe Daull, Nicolas Cimbolini, Laurence Feraille, Sophie Grillo, Mylène Docquier, Christophe Baudouin, Françoise Brignole-Baudouin, Jean-Sébastien Garrigue

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Karima KessalINSERM UMR 968, CNRS UMR 7210, Institut de la Vision, IHU ForeSight, Sorbonne Université UM80,75012 Paris, France.
Philippe DaullSANTEN SAS, Ophthalmic Innovation Center, 91000 Evry-Couronnes, France.
Nicolas CimboliniIris Pharma SAS, 06610 La Gaude, France.
Laurence FerailleIris Pharma SAS, 06610 La Gaude, France.
Sophie GrilloIris Pharma SAS, 06610 La Gaude, France.
Mylène DocquieriGE3 Genomics Platform, Figu Medical School, University of Geneva, CH-1211 Geneva, Switzerland.
Christophe BaudouinINSERM UMR 968, CNRS UMR 7210, Institut de la Vision, IHU ForeSight, Sorbonne Université UM80,75012 Paris, France.
Françoise Brignole-BaudouinINSERM UMR 968, CNRS UMR 7210, Institut de la Vision, IHU ForeSight, Sorbonne Université UM80,75012 Paris, France.ORCID 0000-0002-2006-5384
Jean-Sébastien GarrigueSANTEN SAS, Ophthalmic Innovation Center, 91000 Evry-Couronnes, France.
Centre National de la Recherche Scientifique · FRSanten (France) · FRUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal of this study was to explore the specific signaling pathways related to inflammation in two experimental mouse dry eye (EDE) models. Female C57BL/6 mice housed for 10 days in a controlled desiccative environment were either treated with scopolamine (EDE-1;

Indexed as

Disease Models, AnimalGene Expression RegulationTranscriptomeAdjuvants, AnesthesiaAnimalsCorneaDry Eye SyndromesFemaleInflammation MediatorsLacrimal ApparatusMiceMice, Inbred C57BLScopolamineAdjuvants, AnesthesiaInflammation MediatorsScopolaminebiomarkersdry eye mouse modelinflammatory signaling pathways

Identifiers

PMID34639111
PMCPMC8509332
OpenAlexW3202658637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.