Evidence map›Paper›PMID 34638974›Full record

ArticleInternational journal of molecular sciences2021

Immunostimulatory Potential of Extracellular Vesicles Isolated from an Edible Plant,

Jeong Moo Han, Ha-Yeon Song, Seung-Taik Lim, Kwang-Il Kim, Ho Seong Seo, Eui-Baek Byun

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Green nanomedicine for cancer therapy.Chinese medical journal · 2026
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  18. Recognition on pharmacodynamic ingredients of natural products.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeong Moo HanAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Korea.
Ha-Yeon SongAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Korea.
Seung-Taik LimDepartment of Biotechnology, College of Life Science and Biotechnology, Korea University, Seoul 02841, Korea.
Kwang-Il KimAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Korea.
Ho Seong SeoAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Korea.ORCID 0000-0002-7103-1344
Eui-Baek ByunAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Korea.

Funding

National Research Foundation of Korea NRF-2019R1C1C1002484Nuclear R&D Program of Ministry of Science and ICT Nuclear R&D Program of Ministry of Science and ICT
6 · The paper itself

Abstract

Extracellular vesicles (EVs) have recently been isolated from different plants. Plant-derived EVs have been proposed as potent therapeutics and drug-delivery nanoplatforms for delivering biomolecules, including proteins, RNAs, DNAs, and lipids. Herein,

Indexed as

Adjuvants, ImmunologicAnimalsCD8-Positive T-LymphocytesCell DifferentiationCell ProliferationCells, CulturedCytokinesDendritic CellsExtracellular VesiclesFemaleLymphocyte ActivationMAP Kinase Signaling SystemMiceMice, Inbred BALB CMice, Inbred C57BLMitogen-Activated Protein KinasesAdjuvants, ImmunologicCytokinesMitogen-Activated Protein KinasesNF-kappa Bdendritic cellsextracellular vesiclesimmunostimulatoryPetasites japonicusT cells

Identifiers

PMID34638974
PMCPMC8508627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.