Evidence map›Paper›PMID 34638964›Full record

ArticleInternational journal of molecular sciences2021

DNA Binding Mode Analysis of a Core-Extended Naphthalene Diimide as a Conformation-Sensitive Fluorescent Probe of G-Quadruplex Structures.

Chiara Platella, Rosa Gaglione, Ettore Napolitano, Angela Arciello, Valentina Pirota, Filippo Doria, Domenica Musumeci, Daniela Montesarchio

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Chiara PlatellaDepartment of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0002-6997-1767
Rosa GaglioneDepartment of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.
Ettore NapolitanoDepartment of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.
Angela ArcielloDepartment of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.
Valentina PirotaDepartment of Chemistry, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-6683-1726
Filippo DoriaDepartment of Chemistry, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-1308-1060
Domenica MusumeciDepartment of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0001-7624-1933
Daniela MontesarchioDepartment of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0001-6295-6911
University of Naples Federico II · ITIstituto Nazionale Biostrutture e Biosistemi · ITUniversity of Pavia · ITInstitute of Biostructure and Bioimaging · IT

Funding

Associazione Italiana per la Ricerca sul Cancro IG2020 n. 25046
6 · The paper itself

Abstract

G-quadruplex existence was proved in cells by using both antibodies and small molecule fluorescent probes. However, the G-quadruplex probes designed thus far are structure- but not conformation-specific. Recently, a core-extended naphthalene diimide (

Indexed as

G-QuadruplexesMolecular ConformationAdenocarcinomaBinding SitesBreast NeoplasmsCell SurvivalDNA, B-FormFemaleFluorescent DyesHumansImidesInhibitory Concentration 50Intercalating AgentsLigandsMagnetic Resonance SpectroscopyMCF-7 CellsDNA, B-FormFluorescent DyesImidesIntercalating AgentsLigandsnaphthalenediimideNaphthalenesconformation-sensitive detectionfluorescent probeG-quadruplexnaphthalene diimide

Identifiers

PMID34638964
PMCPMC8508963
OpenAlexW3204633141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.