Evidence map›Paper›PMID 34638959›Full record

ArticleInternational journal of molecular sciences2021

Antitumor Effect of Morusin via G1 Arrest and Antiglycolysis by AMPK Activation in Hepatocellular Cancer.

Ah-Reum Cho, Woon-Yi Park, Hyo-Jung Lee, Deok-Yong Sim, Eunji Im, Ji-Eon Park, Chi-Hoon Ahn, Bum-Sang Shim, Sung-Hoon Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Natural products targeting glycolysis in cancer.Frontiers in pharmacology · 2022
    Pooled it
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  15. Chitosan Nanoparticle-Mediated Delivery ofAntioxidants (Basel, Switzerland) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ah-Reum ChoMolecular Cancer Target Herbal Research Laboratory, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Woon-Yi ParkMolecular Cancer Target Herbal Research Laboratory, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Hyo-Jung LeeMolecular Cancer Target Herbal Research Laboratory, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Deok-Yong SimMolecular Cancer Target Herbal Research Laboratory, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Eunji ImMolecular Cancer Target Herbal Research Laboratory, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Ji-Eon ParkMolecular Cancer Target Herbal Research Laboratory, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Chi-Hoon AhnMolecular Cancer Target Herbal Research Laboratory, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Bum-Sang ShimMolecular Cancer Target Herbal Research Laboratory, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Sung-Hoon KimMolecular Cancer Target Herbal Research Laboratory, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0003-2423-1973
Kyung Hee University · KR

Funding

Korea Science and Engineering Foundation 2020R1A2C2003277Rural Development Administration PJ016252012021
6 · The paper itself

Abstract

Though Morusin isolated from the root of

Indexed as

AMP-Activated Protein KinasesAntineoplastic AgentsCarcinoma, HepatocellularCarrier ProteinsCell Line, TumorCell SurvivalFlavonoidsG1 Phase Cell Cycle CheckpointsGlycolysisHexokinaseHumansLactate Dehydrogenase 5Liver NeoplasmsMAP Kinase Signaling SystemMembrane ProteinsMorusAMP-Activated Protein KinasesAntineoplastic AgentsCarrier ProteinsFlavonoidsHexokinaseHK2 protein, humanLactate Dehydrogenase 5Membrane ProteinsmorusinMTOR protein, humanPlant ExtractsThyroid Hormone-Binding ProteinsThyroid HormonesTOR Serine-Threonine KinasesAMPKG1 arrestglycolysisliver cancerMorusin

Identifiers

PMID34638959
PMCPMC8508967
OpenAlexW3202540006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.