Evidence map›Paper›PMID 34638906›Full record

ReviewInternational journal of molecular sciences2021

Performance of Polydopamine Complex and Mechanisms in Wound Healing.

Dantong Zheng, Chongxing Huang, Xuhao Zhu, Haohe Huang, Chenglong Xu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. From melanogenesis to melanin technologies.Communications chemistry · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dantong ZhengSchool of Light Industry & Food Engineering, Guangxi University, Daxue Road 100, Nanning 530000, China.ORCID 0000-0002-1994-0540
Chongxing HuangSchool of Light Industry & Food Engineering, Guangxi University, Daxue Road 100, Nanning 530000, China.ORCID 0000-0002-4368-9499
Xuhao ZhuSchool of Light Industry & Food Engineering, Guangxi University, Daxue Road 100, Nanning 530000, China.ORCID 0000-0002-2089-4510
Haohe HuangSchool of Light Industry & Food Engineering, Guangxi University, Daxue Road 100, Nanning 530000, China.
Chenglong XuSchool of Light Industry & Food Engineering, Guangxi University, Daxue Road 100, Nanning 530000, China.
Guangxi University · CN

Funding

Guangxi Key R & D Projects of China 2018AB45007National Natural Science Foundation of China 2019JJD120012
6 · The paper itself

Abstract

Polydopamine (PDA) has been gradually applied in wound healing of various types in the last three years. Due to its rich phenol groups and unique structure, it can be combined with a variety of materials to form wound dressings that can be used for chronic infection, tissue repair in vivo and serious wound healing. PDA complex has excellent mechanical properties and self-healing properties, and it is a stable material that can be used for a long period of time. Unlike other dressings, PDA complexes can achieve both photothermal therapy and electro activity. In this paper, wound healing is divided into four stages: antibacterial, anti-inflammatory, cell adhesion and proliferation, and re-epithelialization. Photothermal therapy can improve the bacteriostatic rate and remove reactive oxygen species to inhibit inflammation. Electrical signals can stimulate cell proliferation and directional migration. With low reactive oxygen species (ROS) levels, inflammatory factors are down-regulated and growth factors are up-regulated, forming regular collagen fibers and accelerating wound healing. Finally, five potential development directions are proposed, including increasing drug loading capacity, optimization of drug delivery platforms, improvement of photothermal conversion efficiency, intelligent electroactive materials and combined 3D printing.

Indexed as

BandagesAnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsCell AdhesionCell ProliferationHumansIndolesMolecular StructurePolymersWound HealingAnti-Bacterial AgentsAnti-Inflammatory AgentsIndolespolydopaminePolymersantibacterialelectrical stimulationinflammationphotothermalpolydopamine

Identifiers

PMID34638906
PMCPMC8508909
OpenAlexW3202030687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.