Evidence map›Paper›PMID 34638893›Full record

ReviewInternational journal of molecular sciences2021

Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature).

Beata Smolarz, Krzysztof Szyłło, Hanna Romanowicz

2 registry-linked trialsAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 258 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
258citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06460376 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Comparative Effects of Wurn Technique and Mercier Therapy on Dyspareunia, Dysmenorrhea, and Quality of Life in Women With Endometriosis

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2024Enrolled26ConditionsEndometriosisArmsWurn Technique, Mercier Therapy
NCT07035522 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Evaluation of the Effects of Ozone Therapy on Endometriosis

TypeinterventionalSponsorUniversidade Federal do ParanáRan2025 to 2025Enrolled40ConditionsEndometriosis, Ozone Therapy, ThermographyArmsOzone therapy
3 · Its place in the literature

Who cites it

258 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Article
  10. Review
  11. Therapeutic Potential of Linalool in Endometriosis: Modulation of Oxidative Stress, Inflammation, and Apoptosis in a Rat Model.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Predictive markers of endometriosis: a future perspective.Archives of gynecology and obstetrics · 2026
    Review
  17. Review
  18. Article
  19. Article
  20. Review

198 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Beata SmolarzLaboratory of Cancer Genetics, Department of Pathology, Polish Mother's Memorial Hospital Research Institute, Rzgowska 281/289, 93-338 Lodz, Poland.ORCID 0000-0003-3168-062X
Krzysztof SzyłłoDepartment of Operative Gynaecology and Oncological Gynaecology, Polish Mother's Memorial Hospital Research Institute, Rzgowska 281/289, 93-338 Lodz, Poland.ORCID 0000-0001-7198-4957
Hanna RomanowiczLaboratory of Cancer Genetics, Department of Pathology, Polish Mother's Memorial Hospital Research Institute, Rzgowska 281/289, 93-338 Lodz, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis is a "mysterious" disease and its exact cause has not yet been established. Among the etiological factors, congenital, environmental, epigenetic, autoimmune and allergic factors are listed. It is believed that the primary mechanism of the formation of endometriosis foci is retrograde menstruation, i.e., the passage of menstrual blood through the fallopian tubes into the peritoneal cavity and implantation of exfoliated endometrial cells. However, since this mechanism is also observed in healthy women, other factors must also be involved in the formation of endometriosis foci. Endometriosis is in many women the cause of infertility, chronic pain and the deterioration of the quality of life. It also represents a significant financial burden on health systems. The article presents a review of the literature on endometriosis-a disease affecting women throughout the world.

Indexed as

Gene Expression RegulationAdultCyclooxygenase 2CytokinesEndometriosisEndometriumFemaleHumansInfertility, FemaleVascular Endothelial Growth Factor ACyclooxygenase 2CytokinesVascular Endothelial Growth Factor Abiomarkersdiagnosticendometriosisgenestreatment

Identifiers

PMID34638893
PMCPMC8508982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.